TITLE

Isolation and Identification of Two Compounds of Enhancing Fibrinolysis from Sargassum fulvellum

AUTHOR(S)
LU Wei; WU Wen-hui; ZHOU Pei-gen; BAO Bin
PUB. DATE
October 2009
SOURCE
Natural Product Research & Development;Oct2009, Vol. 21 Issue 5, p787
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The isolation,determination of fibrinolytic activities and structures of compounds were assayed by solvent extraction and successive chromatographic fraction using silica gel, the method of chromogenic substrate in vitro and 1D NMR(¹H,13C, DEPT) and 2D NMR(¹H-1 H COSY, HSQC, HMBC), respectively. We obtained six compounds from Sar-gassum fulvellum and discovered the enhancing fibrinolytic effect of compound B elevated 10%-30% ,but compound D with a slight lower activation of fibrinolysis. By analysis of NMR spectrum compounds B and D were confirmed as palmi-toyl-oleoyl-3-O-&alpha-D-glucopyranosylglycerol and myristoyl-oleoyl-3-O-α-D-glucopyranosylglycerol. Compounds B and D gained from Sargassum fulvellum were designated glycolipid compounds, and myristoyl-oleoyl-3-O-α-D-glucopyranosylg-lycerol was obtained from Sargassum fidvellum for the first time.
ACCESSION #
48077729

 

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics