Drug costs and utilization after implementation of a posaconazole prophylaxis protocol in adults with acute myelogenous leukemia
- Effect of topical oral G-CSF on oral mucositis: a randomised placebo-controlled trial. Karthaus, M; Rosenthal, C; Huebner, G; Paul, H; Elser, C; Hertenstein, B; Krauter, J; Scharmann, T; Geissler, R G; Heil, G; Ganser, A // Bone Marrow Transplantation;10/15/98, Vol. 22 Issue 8, p781
Oral mucositis is a dose-limiting toxicity of intensive chemotherapy. It is caused directly by the cytotoxic effect of chemotherapeutic agents and indirectly by sustained neutropenia. Severe oral mucositis is an important predisposing factor for life-threatening septic complications during...
- A single dose of pegfilgrastim compared with daily filgrastim for supporting neutrophil recovery in patients treated for low-to-intermediate risk acute myeloid leukemia: results from a randomized, double-blind, phase 2 trial. Sierra, Jorge; Szer, Jeffrey; Kassis, Jeannine; Herrmann, Richard; Lazzarino, Mario; Thomas, Xavier; Noga, Stephen J.; Baker, Nigel; Dansey, Roger; Bosi, Alberto // BMC Cancer;2008, Vol. 8, Special section p1
Background: Patients with acute myeloid leukemia (AML) are often neutropenic as a result of their disease. Furthermore, these patients typically experience profound neutropenia following induction and/or consolidation chemotherapy and this may result in serious, potentially lifethreatening,...
- Erythematous eruption in a man with acute myeloid leukemia. Tay, Jason // CMAJ: Canadian Medical Association Journal;9/17/2002, Vol. 167 Issue 6, p672
Presents the case of a man with type two diabetes mellitis who was diagnosed with acute myeloid leukemia. Conventional induction chemotherapy which was given to the patient; Bone marrow suppression resulting from the treatment, which may cause profound neutropenia; Skin rash which was developed...
- Positive impact of selective outpatient management of high-risk acute myelogenous leukemia on the incidence of septicemia. TY Halim; KW Song; MJ Barnett; DL Forrest; DE Hogge; SH Nantel; TJ Nevill; JD Shepherd; CA Smith; HJ Sutherland; CL Toze; JC Lavoie // Annals of Oncology;Jul2007, Vol. 18 Issue 7, p1246
Background: Curative intent chemotherapy for acute myelogenous leukemia (AML) leads to prolonged severe neutropenia, during which patients are highly susceptible to infection. Traditionally these high-risk patients were treated as inpatients. Our center recently implemented a selective...
- Clofarabine. // Reactions Weekly;10/22/2011, Issue 1374, p14
The article describes the case of a 65-year-old man who developed acute renal failure and proteinuria while on clofarabine therapy for a relapse of acute myeloid leukaemia (AML).
- Tocilizumab. // Reactions Weekly;2/11/2012, Issue 1388, p29
The article describes the case of a 40-year-old woman who underwent stem cell transplantation for acute myeloid leukaemia and developed exacerbated hyperbilirubinaemia following the initial intravenous infusion of tocilizumab.
- Intensive Chemotherapy for Acute Myelogenous Leukemia. Gale, Robert Peter; Foon, Kenneth A.; Cline, Martin J.; Zighelboim, Jacob // Annals of Internal Medicine;Jun81, Vol. 94 Issue 6, p753
Presents a study that examined remission rates in a group of patients with acute myelogenous leukemia treated with high-dose induction chemotherapy. Medical history of the patients; Identification of factors that affect remission; Results and discussion.
- Phase II study of carboplatin in blast crisis of chronic myeloid leukemia: Eastern Cooperative Oncology Group Study E1992. Dutcher, J P; Lee, S; Paietta, E; Bennett, J M; Stewart, J A; Wiernik, P H // Leukemia (08876924);Jul98, Vol. 12 Issue 7, p1037
This study was a phase II evaluation of the activity of carboplatin in patients with Philadelphia chromosome positive accelerated or blastic phase of CML. Carboplatin, 250 mg/m[SUP2]/day as an intravenous continuous infusion was given for 5 days, for a total dose of 1250 mg/m[SUP2] per course....
- Analysis of CD34 populations in mobilised peripheral blood stem cell harvests and in bone marrow by fluorescent in situ hybridisation for the bcr/abl gene fusion in patients with chronic granulocytic leukaemia. Irving, J A E; Lennard, A; Storey, N; Conn, J; Dunn, J; Oliver, K; Proctor, S J; Dickinson, A M // Leukemia (08876924);Jun99, Vol. 13 Issue 6, p944
For those patients ineligible for allogeneic bone marrow transplant and who are non-responsive to interferon, autotransplant with peripheral blood stem cells (PBSC) mobilised after intensive chemotherapy, may provide a novel approach to improve prognosis in patients with chronic granulocytic...