New drugs and dosage forms
- Chenic acid for gall stones. // British Medical Journal;9/23/1978, Vol. 2 Issue 6141, p847
Examines the prescription of chenic acid for treating cholesterol gallstones. Increase of proportion of chenic acid in bile during treatment; Cause on the reduction of cholesterol secretion in bile; Dosage of treatment per day.
- Low-cholesterol diet: enhancement of effect of CDCA in patients with gall stones. Maudgal, D.P.; Bird, R.; Blackwood, W.S.; Northfield, T.C. // British Medical Journal;9/23/1978, Vol. 2 Issue 6141, p851
Examines the enhancement of effect of chenodeoxycholic acid in patients with gallstones by a low-cholesterol diet. Effects on the alteration of cholesterol and plant sterol intakes; Composition of low and normal cholesterol diets; Dosage of treatment for resistant patients.
- Optimal timing of doses of chenic acid in patients with gall stones. Maudgal, D.P.; Bird, R.; Northfield, T.C. // British Medical Journal;4/7/1979, Vol. 1 Issue 6168, p922
Investigates the efficacy of optimal timing of doses of chenic acid in patients with gall stones. Factor affecting the enhance effect obtained with bedtime administration; No significant difference in side effects between the three different dose timings; Proportion of bile acids present in the...
- Chenodiol (Chenodeoxycholic Acid) for Dissolution of Gallstones: The National Cooperative Gallstone Study. Schoenfield, Leslie J.; Lachin, John M. // Annals of Internal Medicine;Sep81, Vol. 95 Issue 3, p257
Presents a study that determined the efficacy and safety of randomly allocated chenodeoxyholic acid for the dissolution of radiolucent gallstones. Methodology; Results; Discussion.
- Choosing patients for chenodeoxcholic acid treatment. // British Medical Journal;4/30/1977, Vol. 1 Issue 6069, p1119
Examines the effectiveness of oral chenodeoxycholic acid on gallstones dissolution. Need to identify the response of patients to chenodeoxycholic acid; Factors considered for identifying patients for chenodeoxycholic acid treatment; Effect of the treatment on patients with biliary tract...
- Progress in Dissolving Gallstones. // British Medical Journal;3/29/75, Vol. 1 Issue 5960, p699
Reports the effectivity of gallstone-dissolving agent chenodeoxycholic acid. Suppression of the synthesis of cholesterol by liver; Reduction of the fasting plasma triglyceride level; Estimation of the cholesterol saturation of bile aspirated from duodenum.
- Resistance to chenodeoxycholic acid (CDCA) treatment in obese patients with gall stones. Iser, J.H.; Maton, Paul N.; Murphy, Gerard M.; Dowling, R. Hermon // British Medical Journal;6/10/1978, Vol. 1 Issue 6126, p1509
In most patients with radiolucent gall stones who were given chenodeoxycholic acid (CDCA) in doses of 13-15 mg/kg body weight/day the bile became unsaturated in cholesterol, and their gall stones dissolved. The patients whose stones did not dissolve were significantly heavier and fatter than the...
- MEDICAL NEWS. Havard, J.D.J. // British Medical Journal (Clinical Research Edition);9/15/1984, Vol. 289 Issue 6446, p702
Reporst developments related to medical sciences as of September 1984. Trial of chenodeoxycholic acid for dissolving stones; Application of growth hormones for treatment of short children; Hospital admission of a boy due cystic mass in the abdominal cavity.
- Gall stone dissolving agents. Bouchier, Ian A.D. // British Medical Journal (Clinical Research Edition);3/5/1983, Vol. 286 Issue 6367, p778
Examines the dissolving agents of gall stones in Great Britain. Effectiveness of chenodeoxycholic acid and ursodeoxycholic acid in treating gall stones; Ability of chenodeoxycholic acid to expand the total bile salt pool; Occurrence of radiologically non-visualized gall bladder.