TITLE

Use of multiattribute utility theory for formulary management in a health system

AUTHOR(S)
SEONYOUNG CHUNG; SOOYON KIM; JEONGMEE KIM; KIEHO SOHN
PUB. DATE
January 2010
SOURCE
American Journal of Health-System Pharmacy;1/15/2010, Vol. 67 Issue 2, p128
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Purpose. The application, utility, and flexibility of the multiattribute utility theory (MAUT) when used as a formulary decision methodology in a Korean medical center were evaluated. Methods. A drug analysis model using MAUT consisting of 10 steps was designed for two drug classes of dihydropyridine calcium channel blockers (CCBs) and angiotensin II receptor blockers (ARBs). These two drug classes contain the most diverse agents among cardiovascular drugs on Samsung Medical Center's drug formulary. The attributes identified for inclusion in the drug analysis model were effectiveness, safety, patient convenience, and cost, with relative weights of 50%, 30%, 10%, and 10%, respectively. The factors were incorporated into the model to quantify the contribution of each attribute. For each factor, a utility scale of 0-100 was established, and the total utility score for each alternative was calculated. An attempt was made to make the model adaptable to changing health care and regulatory circumstances. Results. The analysis revealed amlodipine besylate to be an alternative agent, with the highest total utility score among the dihydropyridine CCBs, while barnidipine hydrochloride had the lowest score. For ARBs, losartan potassium had the greatest total utility score, while olmesartan medoxomil had the lowest. Conclusion. A drug analysis model based on the MAUT was successfully developed and used in making formulary decisions for dihydropyridine CCBs and ARBs for a Korean health system. The model incorporates sufficient utility and flexibility of a drug's attributes and can be used as an alternative decision-making tool for formulary management in health systems.
ACCESSION #
47921726

 

Related Articles

  • A Comparative Evaluation of Amlodipine and Hydrochlorothiazide as Monotherapy in the Treatment of Isolated Systolic Hypertension in the Elderly. Herrera, J.; Calvo, C.; Macías, J.; Gude, F.; Sagastagoitia, T.; Abellán, J.; Ferro, B.; Oliván, J.; Vega, A.; Olmos, M.; Martínez, J.; Pita, L.; Sánz, D.; Sarasa, J.; Bueno, J. // Clinical Drug Investigation;2000, Vol. 19 Issue 5, p317 

    Objective: The purpose of this 8-week, randomised, single-blind, parallel group, multicentre, comparative study was to evaluate the efficacy, safety and tolerability of the dihydropyridine calcium antagonist amlodipine versus the thiazide diuretic hydrochlorothiazide for control of isolated...

  • Amlodipine/Valsartan Single-Pill Combination: A Review of its Use in the Management of Hypertension. Frampton, James E.; Scott, Lesley J. // American Journal of Cardiovascular Drugs;2009, Vol. 9 Issue 5, p309 

    Single-pill combinations of the dihydropyridine calcium channel blocker (CCB) amlodipine and the angiotensin II receptor blocker valsartan (amlodipine/valsartan) [Exforge®] are available in the US for the treatment of patients with hypertension. Prescribing information for...

  • Compliance with Antihypertensive Therapy in the Elderly: A Comparison of Fixed-Dose Combination Amlodipine/Benazepril versus Component-Based Free-Combination Therapy. Dickson, Michael; Plauschinat, Craig A. // American Journal of Cardiovascular Drugs;2008, Vol. 8 Issue 1, p45 

    BACKGROUND: Treatment regimens that require fewer dosage units and less frequent dosing to decrease the complexity and cost of care are among the strategies recommended to improve compliance with antihypertensive therapy. Simplifying therapy may be particularly important for elderly patients,...

  • ACE/CCB or ACE/HCTZ for HTN: Which is better? Kuritzky, Louis // Clinical Oncology Alert;Feb2009 Supplement, Vol. 14 Issue 2, p4 

    The article discusses research being done on outcomes in high-risk hypertensive (HTN) patients. It references a study by K. Jamerson et al published in a 2008 issue of the "New England Journal of Medicine." Subjects in this study are considered high-risk due to substantial comorbidity. Their...

  • Special Subgroups in Hypertension: Obese Hypertensives. Kuritzky, Louis // OB/GYN Clinical Alert;May2013, Vol. 30 Issue 1, p9 

    The article discusses the interrelation between obesity, hypertension and cardiovascular (CV) diseases and also informs about a report suggesting that people with existing CV diseases are exposed to greater risk than the obese.

  • Economy keeps health care jobs from heeling. Fredrickson, Tom // Crain's New York Business;02/05/2001, Vol. 17 Issue 6, p22 

    Reports the increase of health care jobs in New York. Factor affecting the merger of clinical facilities; Coverage of health services offered by private hospitals; Recruitment of positions by Health and Hospitals Corporation.

  • MALAYSIA.  // Medical Device Technology;Nov2002, Vol. 13 Issue 9, p80 

    Announces the construction of a medical facility in the district of Pendang in Malaysia, which will include four-bed day care and four-bed maternity wards, a rehabilitation room, pharmacy and laboratory.

  • WEB EXCLUSIVES.  // Health Facilities Management;Jun2011, Vol. 24 Issue 6, p6 

    The article presents news briefs on the health care industry, including the maintenance of health care facility floor, planning of a hybrid operating room and the benefits of health facility commissioning.

  • Del Webb Foundation gives St. Rose Dominican project $3M. Reed, Vita // Las Vegas Business Press;04/06/98, Vol. 15 Issue 14, p22 

    Presents updates on the health industry in Las Vegas, Nevada. Amount that will be received by Saint Rose Dominican Hospital from the Del E. Webb Foundation; Why the US EnviroMedical Corporation changed Dennis Dantzik, its top executive; Details on the 1997 activity report released by the Nevada...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics