Crux of drug compatibility and incompatibility

Newton, David W.
January 2010
American Journal of Health-System Pharmacy;1/15/2010, Vol. 67 Issue 2, p108
Academic Journal
The article presents information on the physical and chemical factors responsible for drug compatibility. The crux is one of such factors that enables the drug to be classified as either acid cations or basic anions depending on its salt content. The patient should refrain from taking mixtures of opposite drug ions to avoid any drug incompatibility. Amphoteric, like-charged drugs and in situ salts lacking a non-drug ion are few exceptions of the crux.


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