Nephroblastoma in adults. Clinical and histopathological features of two incidental Wilms' tumors

Wroński, Stanislaw; Marszałek, Andrzej
September 2009
Central European Journal of Urology;Sep2009, Vol. 62 Issue 3, p198
Academic Journal
Nephroblastoma (Wilms' tumor) - the most common malignant renal tumor in childhood is extremely rare in adults. Early diagnosis is difficult and usually made by pathologic examination of a surgical specimen. The possibility of successful treatment and therefore prognosis of nephroblastoma in adults is poorer when compared with results in children. Here authors report 2 cases of nephroblastoma incidentally diagnosed in adult age and demonstrate the diagnostic challenges and distinct histopathological features of nephroblastomas in the adult age group. Authors present results of imaging diagnostic techniques and histopathological as well as immunohistochemical findings. As a result of analysis of clinical data, histopathological findings, and immunohistochemical results both analyzed patients were regarded as cases meeting criteria of favorable histology with low or intermediate risk of progression.


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