Chlamydia trachomatis causing neonatal conjunctivitis in a tertiary care center

Kakar, S.; Bhalla, P.; Maria, A.; Rana, M.; Chawla, R.; Mathur, N. B.
January 2010
Indian Journal of Medical Microbiology;Jan2010, Vol. 28 Issue 1, p45
Academic Journal
Chlamydia trachomatis is considered a major aetiological agent of conjunctivitis in newborns. The objective of the present study was to determine the aetiology of neonatal conjunctivitis and clinico-epidemiological correlates of chlamydial ophthalmia neonatorum. Fifty-eight newborns with signs and symptoms of conjunctivitis were studied. Conjunctival specimens were subjected to Gram staining, routine bacteriological culture, culture for Neisseria gonorrhoeae and direct fluorescent antibody (DFA) staining for diagnosis of C. trachomatis infection. C. trachomatis was detected in 18 (31%) neonates. Findings suggest that since C. trachomatis is the most common cause of neonatal conjunctivitis, routine screening and treatment of genital C. trachomatis infection in pregnant women and early diagnosis and treatment of neonatal Chlamydial conjunctivitis may be considered for its prevention and control.


Related Articles

  • Neonatal Chlamydial Infections: Prevention and Treatment. Zar, Heather J. // Pediatric Drugs;2005, Vol. 7 Issue 2, p103 

    Neonatal chlamydial infection, which manifests principally as ophthalmia neonatorum (ON) or pneumonia, is a significant cause of neonatal morbidity. Widespread use of silver nitrate drops resulted in a dramatic decline in the incidence of gonococcal ophthalmia but had much less impact on the...

  • Ophthalmia neonatorum: a vanishing disease or underreported notification? Pilling, R.; Long, V.; Hobson, R.; Schweiger, M. // Eye;Sep2009, Vol. 23 Issue 9, p1879 

    The article presents a case study of Ophthalmia neonatorum, a conjunctival infection within the first 28 days of life and is commonly used to refer to those cases caused by Neisseria gonorrhoeae or Chlamydia trachomatis. It notes that Ophthalmia neonatorum is a notifiable disease in England and...

  • The Use of Polymerase Chain Reaction Assay versus Cell Culture in Detecting Neonatal Chlamydial Conjunctivitis. Rafiei Tabatabaei, Sedigheh; Abolfazl Afjeiee, Seyed; Tahami Zanjani, Nafiseh; Shiva, Farideh; Tavakkoly Fard, Arezou; Reza Shamshiri, Ahmad; Karimi, Abdollah // Archives of Iranian Medicine (AIM);Mar2012, Vol. 15 Issue 3, p171 

    One of the most common bacterial infections that causes ophthalmia neonatorum is Chlamydia trachomatis, (C. trachomatis). Very few studies have been performed in Iran using both cell culture and polymerase chain reaction (PCR) methods to determine the prevalence of C. trachomatis as an...

  • A microbiological study of neonatal conjunctivitis in two hospitals in Tehran, Iran. Afjeiee, Seyed Abolfazl; Tabatabaei, Sedigheh Rafiei; Fallah, Fatemeh; Fard, Arezou Tavakkoly; Shiva, Farideh; Adabian, Saadat; Karimi, Abdollah // BMC Infectious Diseases;2012 Supplement, Vol. 12 Issue Supplment 1, p1 

    The article presents a microbiological study on the prevalence of neonatal conjunctivitis in Tehran, Iran. The authors aims to identify the common causative agent of the eye infections in newborns. They indicate that Gram Positive Cocci and Chlamydia trachomatis are the most common organisms...

  • Distribution study of Chlamydia trachomatis genotypes in symptomatic patients in Buenos Aires, Argentina: association between genotype E and neonatal conjunctivitis. Vaulet, Lucía Gallo; Entrocassi, Carolina; Corominas, Ana I.; Fermepin, Marcelo Rodríguez // BMC Research Notes;2010, Vol. 3, p34 

    Background: Chlamydia trachomatis infections are the most prevalent sexually transmitted bacterial infections in the world. There is scarce data available referring to the distribution of C. trachomatis genotypes in Argentina. The aim of this study was to identify the genotypes of C. trachomatis...

  • NEED-TO-KNOW BASIS: pinkeye.  // Baby Talk;Sep2011, Vol. 76 Issue 7, p32 

    The article offers information on pinkeye, or conjunctivitis, which is the common eye infection in children caused by a variety of bacteria.

  • A Case of Infantile Conjunctivitis. Shovlin, Joseph P. // Review of Optometry;9/15/2002, Vol. 139 Issue 9, p105 

    Presents a question and answer advisory on infantile conjunctivitis. Development of ophthalmia neonatorum from chlamydia trachomatis; Diagnosis of the abnormalities through culturing of swabs of the conjunctiva; Treatment of patient with copious irrigation.

  • Comparison of Direct Immunofluorescence and Giemsa Staining in Chlamydia trachomatis Follicular Conjunctivitis. Asadi-Amoli, Fahimeh; Nozarian, Zohreh; Mehrtash, Vahid; Beheshtnejad, Hooshang; Shabani, Avishan // Zahedan Journal of Research in Medical Sciences;Oct2015, Vol. 17 Issue 10, p1 

    Background: Chlamydia trachomatis is the most common sexually transmitted bacterial infection and can cause various types of human eye disease. There are two general methods for diagnosis of chlamydial infection; cell culture and non-culture tests. Objectives: In this study we evaluated the...

  • Is Credé's prophylaxis for ophthalmia neonatorum still valid? Schaller, Ulrich C.; Klauss, Volker // Bulletin of the World Health Organization;2001, Vol. 79 Issue 3, p262 

    Examines the validity of Crede's prophylaxis for ophthalmia neonatorum (ON) or neonatal conjunctivitis. Etiology of ophthalmia neonatorum; Effectiveness of povidone-iodine in preventing ON; Implication of treating infected pregnant women for the prevention of neonate infection.

  • Infective conjunctivitis.  // Independent Nurse;9/5/2011, p29 

    The article focuses on the management of infective conjunctivitis as commonly caused by bacteria and virus including Hemophilus influenzae, Streptococcus pneumoniae and adenovirus. It reviews the aetiology and epidemiology of infective conjunctivitis, the symptoms and presentation and the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics