TITLE

Extra-corporeal membrane oxygenation temporary support for early graft failure after cardiac transplantation

AUTHOR(S)
D’Alessandro, Cosimo; Aubert, Stéphane; Golmard, Jean Louis; Praschker, Beltran Levy; Luyt, Charles Edouard; Pavie, Alain; Gandjbakhch, Iradj; Leprince, Pascal
PUB. DATE
February 2010
SOURCE
European Journal of Cardio-Thoracic Surgery;Feb2010, Vol. 37 Issue 2, p343
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Abstract: Objective: Early graft failure (EGF) is a major risk for death after heart transplantation. We studied the impact of an extra-corporeal membrane oxygenation (ECMO) temporary support on the operative mortality and the mean-term survival after EGF. Materials and methods: Between January 2000 and December 2006, 394 patients underwent orthotopic heart transplantation at our institution. EGF was observed in 90 (23%) patients. Fifty-four patients (14%) were treated with ECMO support, eight (2%) with other assisting devices, and 28 (7%) received maximal inotropic drug support only. Results: The overall mortality was 21% (83 patients). EGF was a major risk for death: 13% (35 patients) without EGF versus 58% (49 patients) with EGF, p <0001. Among patients supported with ECMO, 36 (67%) were weaned from the assisting device and 27 (50%) were discharged from the hospital. Overall survival was 73% at 1 year and 66% at 5 years. Absence of EGF improved long-term survival: 78% at 1 year and 70% at 5 years without EGF versus 37% at 1 year and 35% at 5 years with EGF. Patients treated with ECMO have the same 1-year conditional survival as patients not having suffered EGF: 94% at 3 years. Conclusions: ECMO support is a reliable therapeutic option in severe EGF after cardiac transplantation; furthermore, patients treated with ECMO have the same 1-year conditional survival as patients not having suffered EGF.
ACCESSION #
47610538

 

Related Articles

  • Humoral rejection after pediatric heart transplantation: a case report. Stendahl, Gail; Berger, Stuart; Ellis, Tom; Gandy, Kimberly; Mitchell, Michael; Tweddell, James; Zangwill, Steven // Progress in Transplantation;Sep2010, Vol. 20 Issue 3, p288 

    Humoral rejection was observed 2 years after heart transplantation in a 10-year-old African American girl with sickle cell disease. Hemodynamic compromise developed, and the patient started treatment with extracorporeal membrane oxygenation within 24 hours of admission. With cellular rejection...

  • Delayed Sternal Closure After Pediatric Cardiac Operations; Single Center Experience: a Retrospective Study. Özker, Imre; Saritaş, Bülent; Vuran, Can; Yörüker, Uygar; Ulugöl, Halim; Türköz, Riza // Journal of Cardiothoracic Surgery;2012, Vol. 7 Issue 1, p102 

    Background: Delayed sternal closure (DSC) after cardiac surgery is a therapeutic option in the treatment of the severely impaired heart in pediatric cardiac surgery. The results with the technique of DSC over a 4-year period are examined with regard to mortality and morbidity .Methods: We...

  • Editorial. Punjabi, Prakash P. // Perfusion;Jan2009, Vol. 24 Issue 1, p5 

    The article discusses various reports published within the issue including one on the successful use of hand-held extracorporeal membrane oxygenation and its long-term use, one on bivalirudin as an anticoagulant for cardiac surgery and another propofol requirement and comparison of hypo- and...

  • Modified T-Graft for Extracorporeal Membrane Oxygenation in a Patient with Small-Caliber Femoral Arteries. Calderon, Daniel; El-Banayosy, Aly; Koerner, Michael M.; Reed, Amy B.; Aziz, Faisal // Texas Heart Institute Journal;Dec2015, Vol. 42 Issue 6, p537 

    Extracorporeal membrane oxygenation (ECMO) is generally used as a last resort to provide cardiopulmonary support in patients whose advanced cardiac or respiratory failure does not respond to less invasive treatments. Lower-limb ischemia secondary to the large diameter of the arterial cannula is...

  • Successful Use of Surgically Placed Impella 5.0 and Central Extracorporeal Membrane Oxygenation Circuit in a Patient with Postcardiotomy Shock. Abu Saleh, Walid K.; Mason, Phillip; Jabbari, Odeaa Al; Samir, Hany; Bruckner, Brian A. // Texas Heart Institute Journal;Dec2015, Vol. 42 Issue 6, p569 

    The Impella 5.0, a percutaneously inserted left ventricular assist device, has been used to support patients who have severe heart failure or who are undergoing high-risk percutaneous coronary intervention. We report our surgical placement of the Impella 5.0, through a graft sewn to the aorta,...

  • Impact of either short- or long-term right heart support on continuous flow LVAD outcomes. Rao, S.; Shehab, S.; Lewis, J.; De Silva, K.; Desiree, R.; Connellan, M.; Macdonald, P.; Keogh, A.; Jabbour, A.; Kotlyar, E.; Granger, E.; Spratt, P.; Dhital, K.; Jansz, P.; Hayward, C. // Heart, Lung & Circulation;2015 Supplement 3, Vol. 24, pS208 

    No abstract available.

  • A review of extracorporeal membrane oxygenation in child after cardiac surgery: analyses of outcomes. Asano, M.; Nakai, Y.; Matsumae, H.; Ukai, T.; Nomura, N.; Mishima, A. // Journal of Cardiothoracic Surgery;2013, Vol. 8 Issue Suppl 1, p1 

    An abstract of the article "A review of extracorporeal membrane oxygenation in child after cardiac surgery: analyses of outcomes" by M. Asano and colleagues is presented.

  • Acute kidney injury network classification predicts in-hospital and long-term mortality in patients undergoing elective coronary artery bypass grafting surgery. Li, Szu-Yuan; Chen, Jinn-Yang; Yang, Wu-Chang; Chuang, Chiao-Lin // European Journal of Cardio-Thoracic Surgery;Mar2011, Vol. 39 Issue 3, p323 

    Abstract: Objective: Acute kidney injury (AKI) is a highly prevalent complication after cardiac surgery. It is associated with substantial morbidity and mortality. However, the definition of AKI has not been well established until the Acute Kidney Injury Network group outlined an easily used...

  • Outcome of Veno-Arterial Extracorporeal Membrane Oxygenation for Patients Undergoing Valvular Surgery Wang, Jian-Gang; Han, Jie; Jia, Yi-Xin; Zeng, Wen; Hou, Xiao-Tong; Meng, Xu // PLoS ONE;May2013, Vol. 8 Issue 5, p1 

    Background: We evaluated retrospectively the early and midterm results of using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support in patients undergoing valvular surgery. Methods: A total of 87 patients undergoing valvular surgery received VA-ECMO due to refractory...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics