TITLE

Relationship Between Obesity and Incident Diabetes in Middle-Aged and Older Japanese Adults: The Ibaraki Prefectural Health Study

AUTHOR(S)
Sasai, Hiroyuki; Sairenchi, Toshimi; Iso, Hiroyasu; Irie, Fujiko; Otaka, Emiko; Tanaka, Kiyoji; Ota, Hitoshi; Muto, Takashi
PUB. DATE
January 2010
SOURCE
Mayo Clinic Proceedings;Jan2010, Vol. 85 Issue 1, p36
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
OBJECTIVE: To investigate the age-specific relationship between body mass index (BMI) and risk of diabetes in a Japanese general population. PARTICIPANTS AND METHODS: A cohort of Japanese men (N=19,926) and women (N=41,489) (aged 40-79 years) who under went community-based health checkups in 1993 and were free of diabetes was followed up by annual examinations with measurement of blood glucose concentrations until the end of 2006. Incident diabetes mellitus was defined as a blood glucose concentration of 126 mg/dL or greater under fasting conditions, 200 mg/dL or greater under nonfasting conditions, or diabetic medication use at baseline. Hazard ratios (HRs) for diabetes according to BMI were estimated using a Cox proportional hazard model. The model was adjusted for possible confounding variables. RESULTS: A total of 4429 participants (7.2%) developed diabetes (2065 men and 2364 women) during a mean follow-up of 5.5 years. Compared with those with a BMI of less than 25.0, the multivariate HRs for diabetes among participants with a BMI of 30.0 or greater were 1.40 (95% confidence interval [CI], 0.89-2.20) for men aged 40 to 59 years and 1.26 (95% CI, 0.81-1.96) for men aged 60 to 79 years (P=.002 for interaction). The HRs were 2.50 (95% CI, 2.01-3.11) for women aged 40 to 59 years and 1.80 (95% CI, 1.41-2.30) for women aged 60 to 79 years (P=.04 for interaction). CONCLUSION: The effect of obesity on the risk of diabetes is greater for middle-aged than for older adults.
ACCESSION #
47421466

 

Related Articles

  • Family history of diabetes identifies a group at increased risk for the metabolic consequences of obesity and physical inactivity in EPIC-Norfolk: a population-based study. Sargeant, L A; Wareham, N J; Khaw, K-T // International Journal of Obesity & Related Metabolic Disorders;Oct2000, Vol. 24 Issue 10, p1333 

    OBJECTIVE: To investigate the interaction of a family history of diabetes with obesity and physical inactivity on diabetes prevalence in middle-aged and elderly men and women. DESIGN: A cross-sectional population-based study. SUBJECTS: 2912 men and 3561 women, aged 45–74 y. MEASUREMENTS:...

  • Association among dietary magnesium, serum magnesium, and diabetes: a crosssectional study in middle-aged and older adults. Jie Wei; Chao Zeng; Xiao-xiao Li; Qian-yi Gong; Guang-hua Lei; Tu-bao Yang // Journal of Health, Population & Nutrition;10/18/2016, Vol. 35, p1 

    Background: A number of studies have reported the association between magnesium (Mg) and diabetes. However, the various conclusions were inconsistent and the data on the Chinese population was limited. The objective of this study was to evaluate the association among dietary Mg, serum Mg, and...

  • LONGITUDINAL, BIOMEDICAL STUDIES OF MIDLIFE AND ELDERLY MINORITY ADULTS: DESIGN AND OUTCOMES. Miles, Toni P. // Gerontologist;Oct1996 Supplement, Vol. 36 Issue 1, p356 

    Prior to 1983 there were no large-scale, epidemiologic studies of health and aging which included minority participants. During the past 16 years to fill the need for better data on health and aging in a variety of groups, the National Institute on Aging has funded a number of minority focused...

  • It's Not Too Late for Healthy Changes.  // Tufts University Health & Nutrition Letter;Oct2007, Vol. 25 Issue 8, p8 

    The author reports on research that found that subjects who made lifestyle changes later in life lowered their risk of heart disease and risk for premature death. It was the adoption of four healthy habits that made the most improvement in health in the subjects. Healthy habits included...

  • THE USA NATIONAL STRATEGIC PLAN FOR PROMOTING PHYSICAL ACTIVITY IN THE MID-LIFE AND OLDER ADULT POPULATION. Chodzko-Zajko, Wojtek // Studies in Physical Culture & Tourism;2006 Supplement, Vol. 13, p15 

    On May 1, 2001, a coalition of national organizations released a major planning document designed to develop a national strategy for the promotion of physically active lifestyles among the mid-life and older adult population. The National Blueprint: Increasing Physical Activity Among Adults Age...

  • The Image of Health Food Brands, Experience Recognition and the Purchase Behavior of Middle Aged and Older People. Li-Hsing Ho; Yi Tai; Chia-Ming Chang; Wei-San Su; Jian-Hua Yu; Chun-Chang Yen // Pakistan Journal of Nutrition;2013, Vol. 12 Issue 3, p285 

    Aging societies are a global social trend that simultaneously promotes the development of biotechnology and health food industries. Thus, middle-aged and older people's health food purchase behavior has been widely analyzed. For this study, we sampled Chiayi County, Taiwan, to investigate the...

  • Statins' benefits extend to older patients.  // Geriatrics;Jan2003, Vol. 58 Issue 1, p61 

    Highlights the results of the Prospective Study of Pravastatin in the Elderly at Risk trial, led by James Shepherd, which showed that the benefit of pravastatin in middle-aged populations extends to older people. Effect of pravastatin on incidence of coronary heart disease events, cognition and...

  • Rethinking the Stroke Factor. LYDEN, PATRICK D. // USA Today Magazine;Jul2013, Vol. 142 Issue 2818, p72 

    The article discusses the risk of middle aged and preretirement people for stroke. It mentions that despite the prominence of the health condition in elderly people, everyone should know that stroke can occur at any age. According to the author, 18.6 per cent of people age between 20 to 54...

  • Baseline Health, Socioeconomic Status, and 10-Year Mortality Among Older Middle-Aged Americans: Findings From the Health and Retirement Study, 1992-2002. Feinglass, Joe; Lin, Suru; Thompson, Jason; Sudano, Joseph; Dunlop, Dorothy; Jing Song; Baker, David W. // Journals of Gerontology Series B: Psychological Sciences & Socia;Jul2007, Vol. 62B Issue 4, pS209 

    Objectives. This study analyzed whether socioeconomic status in older middle age continues to be associated with 10-year survival after data are controlled for baseline health status. Methods. We confirmed deaths through 2002 for 9,759 participants in the Health and Retirement Study, aged 51 to...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics