TITLE

SSRIs in early pregnancy were associated with increased risk for septal heart defects but not major congenital malformations overall

AUTHOR(S)
Koren, Gideon
PUB. DATE
December 2009
SOURCE
ACP Journal Club;12/15/2009, Vol. 151 Issue 6, p13
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents information about a study which analyzes whether the use of selective serotonin reuptake inhibitors (SSRIs) in early pregnancy increases the risk for congenital malformations. 496,881 singleton live-born children born during 1996-2003 were studied. The results show that SSRIs taken during the first trimester of pregnancy were not associated with increased risk for major congenital malformations, but they did increase the absolute risk for septal heart defects by 0.4%.
ACCESSION #
47420858

 

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