TITLE

Understanding Analytical Error--The Use of Controls and Blind Controls

AUTHOR(S)
Nunnally, Brian K.; McConnell, John; McGarvey, Bernard
PUB. DATE
November 2009
SOURCE
Journal of Validation Technology;Autumn2009, Vol. 15 Issue 4, p56
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the use of controls and blind controls in laboratories. Quantitative assays can benefit from a control sample. However, a residual assay does not require a control since variability is not as important. When selecting a control sample, it must be representative of the material being tested. It also needs to be stable over time and should be homogeneous. The usage rate, the usability of control and the amount of available material are the factors affecting the amount of materials needed for a control sample. A nice method for determining the suitability of an assay can be provided by a proper control sample combined with robust control charting.
ACCESSION #
47337025

 

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