TITLE

Carcinoma of the middle bile duct: Is bile duct segmental resection appropriate?

AUTHOR(S)
Hyung Geun Lee; Sang Hoon Lee; Dong Do Yoo; Kwang Yeol Paik; Jin Seok Heo; Seong Ho Choi; Dong Wook Choi; Basoli, Antonio
PUB. DATE
December 2009
SOURCE
World Journal of Gastroenterology;12/21/2009, Vol. 15 Issue 47, p5966
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
AIM: To compare survival between bile duct segmental resection (BDSR) and pancreaticoduodenectomy (PD) for treating distal bile duct cancers. METHODS: Retrospective analysis was conducted for 45 patients in a BDSR group and for 149 patients in a PD group. RESULTS: The T-stage (P < 0.001), lymph node invasion (P = 0.010) and tumor differentiation (P = 0.005) were significant prognostic factors in the BDSR group. The 3- and 5-year overall survival rates for the BDSR group and PD group were 51.7% and 36.6%, respectively and 46.0% and 38.1%, respectively (P = 0.099). The BDSR group and PD group did not show any significant difference in survival when this was adjusted for the TNM stage. The 3- and 5-year survival rates were: stage I a [BDSR (100.0% and 100.0%) vs PD (76.9% and 68.4%) (P = 0.226)]; stage I b [BDSR (55.8% and 32.6%) vs PD (59.3% and 59.3%) (P = 0.942)]; stage I b [BDSR (19.2% and 19.2%) vs PD (31.9% and 14.2%) (P = 0.669)]. CONCLUSION: BDSR can be justified as an alternative radical operation for patients with middle bile duct in selected patients with no adjacent organ invasion and resection margin is negative.
ACCESSION #
47336372

 

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