Radionuclides and radiopharmaceuticals for single-photon emission tomography, positron emission tomography and radiotherapy in Russia

Krasikova, Raisa N.; Kodina, Galina E.
July 1999
European Journal of Nuclear Medicine;1999, Vol. 26 Issue 7, p774
Academic Journal
The current status of the manufacture of radiopharmaceuticals for diagnostic and therapeutic application in Russia is discussed, consideration being given to various aspects of the production and distribution of radionuclides, radioisotope generators and kits as well as individual radiopharmaceuticals in different regions of the country. The major focus is on the recent developments in production technologies for therapeutic and single-photon emission tomography radionuclides, technetium chemistry and synthetic approaches for the labelling of compounds with short-lived positron emitters. The status of positron emission tomography and its application are considered. The major factors restricting the expansion of nuclear imaging techniques and radiotherapy in Russia are also discussed.


Related Articles

  • The Role of Non-Standard PET Radionuclides in the Development of New Radiopharmaceuticals. Avila-Rodriguez, M. A.; McQuarrie, S. A. // AIP Conference Proceedings;8/11/2008, Vol. 1032 Issue 1, p25 

    This paper discusses the production methods of the most commonly used non-standard PET radionuclides, their decay characteristics and importance in the development of novel radiopharmaceuticals for PET-based molecular imaging and potential applications in therapy.

  • Technologies for Translational Imaging Using Generators in Oncology. Schechter, Naomi R.; Yang, David J.; Azhdarinia, Ali; Chanda, Mithu // Recent Patents on Anti-Cancer Drug Discovery;Nov2007, Vol. 2 Issue 3, p251 

    Improvement of scintigraphic tumor imaging is extensively determined by the development of more tumor specific radiopharmaceuticals. Thus, to improve the differential diagnosis, prognosis, planning and monitoring of cancer treatment, several functional pharmaceuticals have been developed. The...

  • Fast-Specific Tomography Imaging via Cerenkov Emission. Zhong, Jianghong; Qin, Chenghu; Yang, Xin; Chen, Zhe; Yang, Xiang; Tian, Jie // Molecular Imaging & Biology;Jun2012, Vol. 14 Issue 3, p286 

    Purpose: Development of more tumor-specific radiopharmaceuticals is not enough; to understand the disease, we must study data modeling. Although fluoro-18-deoxyglucose positron emission tomography can map a multi-peak distribution of trace radioisotopes, optical tomography should also be able to...

  • Clinical radionuclide therapy dosimetry: the quest for the “Holy Gray”. Brans, B.; Bodei, L.; Giammarile, F.; Linden, O.; Luster, M.; Oyen, W. J. G.; Tennvall, J. // European Journal of Nuclear Medicine & Molecular Imaging;May2007, Vol. 34 Issue 5, p772 

    Radionuclide therapy has distinct similarities to, but also profound differences from external radiotherapy. This review discusses techniques and results of previously developed dosimetry methods in thyroid carcinoma, neuro-endocrine tumours, solid tumours and lymphoma. In each case, emphasis is...

  • Guidance on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals. Elsinga, Philip; Todde, Sergio; Penuelas, Ivan; Meyer, Geerd; Farstad, Brit; Faivre-Chauvet, Alain; Mikolajczak, Renata; Westera, Gerrit; Gmeiner-Stopar, Tanja; Decristoforo, Clemens // European Journal of Nuclear Medicine & Molecular Imaging;May2010, Vol. 37 Issue 5, p1049 

    This guidance is meant as a guidance to Part B of the EANM “Guidelines on Good Radiopharmacy Practice (GRPP)” issued by the Radiopharmacy Committee of the EANM (see ), covering the small-scale “in house” preparation of radiopharmaceuticals which are not kit procedures....

  • [18F]Ethenesulfonyl Fluoride as a Practical Radiofluoride Relay Reagent. Zhang, Bo; Fraser, Benjamin H.; Klenner, Mitchell A.; Chen, Zhen; Liang, Steven H.; Massi, Massimiliano; Robinson, Andrea J.; Pascali, Giancarlo // Chemistry - A European Journal;6/7/2019, Vol. 25 Issue 32, p7613 

    Fluorine‐18 is the most utilized radioisotope in positron emission tomography (PET), but the wide application of fluorine‐18 radiopharmaceuticals is hindered by its challenging labelling conditions. As such, many potentially important radiotracers remain underutilized. Herein, we...

  • Radiofármacos de galio 68. Morín Zorrilla, José; Cruz Arencibia, Jorge // Nucleus;2012, Issue 51, p1 

    The positron emission tomography is a technique of medical image of great sensibility and high resolution that requires short-lived positron emitting radionuclides. The most commonly used are 18F and 11C. The main difficulty of these radionuclides is the necessity to install a cyclotron in the...

  • Evaluation of a technique for in vivo internal monitoring of 18F within a Brazilian laboratory network. Oliveira, Cássio Miri; Lima, Fabiana Farias; de Oliveira, Mércia Liane; da Silva, Tânia Valéria; Dantas, Ana Letícia; Dantas, Bernardo Maranhão; Alonso, Thêssa C.; da Silva, Teógenes Augusto // Radiation Protection Dosimetry;Jan2013, Vol. 153 Issue 1, p100 

    18FDG, an analogue of glucose labelled with the radionuclide 18F, is the most widely used radiopharmaceutical in positron emission tomography/computed tomography technique. In Brazil, there are currently eight 18FDG plants in operation and other facilities are expected to start their production...

  • Re-emergence of the important role of radionuclide generators to provide diagnostic and therapeutic radionuclides to meet future research and clinical demands. Knapp, F.; Pillai, M.; Osso, J.; Dash, Ashutosh // Journal of Radioanalytical & Nuclear Chemistry;Dec2014, Vol. 302 Issue 3, p1053 

    Radionuclide generators have been the main stay of diagnostic nuclear medicine and it is no exaggeration to state that the growth of nuclear medicine would not have happened to the present levels but for the availability of Mo/Tc generator. This article provides a brief account of the various...

  • Highlights of the XIV Congress of the Polish Society of Nuclear Medicine, Lublin, 28-30th May, 2014. Czepczyński, Rafał // Nuclear Medicine Review;2014, Vol. 17 Issue 2, p123 

    No abstract available.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics