Transmission imaging for registration of ictal and interictal single-photon emission tomography, magnetic resonance imaging and electroencephalography

Sipilä, Outi; Nikkinen, Päivi; Savolainen, Sauli; Granström, Marja-Liisa; Gaily, Eija; Poutanen, Veli-Pekka; Pohjonen, Hanna; Liewendahl, Kristian
February 2000
European Journal of Nuclear Medicine;2000, Vol. 27 Issue 2, p202
Academic Journal
Abstract. A method developed for registration of ictal and interictal single-photon emission tomography (SPET), magnetic resonance imaging (MRI) and electroencephalography (EEG) is described. For SPET studies, technetium-99m ethyl cysteinate dimer (ECD) was injected intravenously while the patient was monitored on video-EEG to document the ictal or interictal state. Imaging was performed using a triple-head gamma camera equipped with a transmission imaging device using a gadolinium-153 source. The images (128x128 pixels, voxel size 3.7x3.7x3.6 mm[sup 3]) were reconstructed using an iterative algorithm and postfiltered with a Wiener filter. The gold-plated silver electrodes on the patient's scalp were utilized as markers for registration of the ictal and interictal SPET images, as these metallic markers were clearly seen on the transmission images. Fitting of the marker sets was based on a non-iterative least squares method. The interictal SPET image was subtracted from the ictal image after scaling. The T1-weighted MPRAGE MR images with voxel size of 1.0x1.0x1.0 mm[sup 3] were obtained with a 1.5-T scanner. For registration of MR and subtraction SPET images, the...


Related Articles

  • Techniques for imaging neuroscience. Turner, Robert; Jones, Terry // British Medical Bulletin;Mar2003, Vol. 65 Issue 1, p3 

    In the last 20 years, a number of non-invasive spatial mapping techniques have been demonstrated to provide powerful insights into the operation of the brain during task performance. These are, in order of their emergence as robust technologies: positron emission tomography, source localization...

  • Finding out what and how.  // Wellness Options;2005, Issue 18, p18 

    Discusses technologies to investigate the secrets and functions of the brain. Electroencephalography; Computed tomography; Positron emission tomography; Functional magnetic resonance imaging.

  • Hope and great opportunity for young neuroscientists. Bashir, Shahid // Pakistan Journal of Medical Sciences;Aug2013, Vol. 29 Issue 4, p897 

    The author reflects on opportunities provided to neuroscientists and neurologists in Asia due to need to improve diagnosis and promote prevention of neurodegenerative diseases and neuropsychiatric disorder. He states that several brain imaging tools including functional magnetic resonance...

  • Advances in Electrophysiological Research. Kamarajan, Chella; Porjesz, Bernice // Alcohol Research: Current Reviews;2015, Vol. 37 Issue 1, p53 

    Electrophysiological measures of brain function are effective tools to understand neurocognitive phenomena and sensitive indicators of pathophysiological processes associated with various clinical conditions, including alcoholism. Individuals with alcohol use disorder (AUD) and their high-risk...

  • All-in-one interictal presurgical imaging in patients with epilepsy: single-session EEG/PET/(f)MRI. Grouiller, Frédéric; Delattre, Bénédicte; Pittau, Francesca; Heinzer, Susanne; Lazeyras, François; Spinelli, Laurent; Iannotti, Giannina; Seeck, Margitta; Ratib, Osman; Vargas, Maria; Garibotto, Valentina; Vulliemoz, Serge // European Journal of Nuclear Medicine & Molecular Imaging;Jun2015, Vol. 42 Issue 7, p1133 

    Purpose: In patients with pharmacoresistant focal epilepsy, resection of the epileptic focus can lead to freedom from seizures or significant improvement in well-selected candidates. Localization of the epileptic focus with multimodal concordance is crucial for a good postoperative outcome....

  • Clinical utility of BOLD fMRI in preoperative work.up of epilepsy. Ganesan, Karthik; Ursekar, Meher // Indian Journal of Radiology & Imaging;Feb2014, Vol. 24 Issue 1, p22 

    Surgical techniques have emerged as a viable therapeutic option in patients with drug refractory epilepsy. Pre-surgical evaluation of epilepsy requires a comprehensive, multiparametric, and multimodal approach for precise localization of the epileptogenic focus. Various non-invasive techniques...

  • DOUBLE VISION.  // Technology Review;Dec2001, Vol. 104 Issue 10, p19 

    Reports the development of a combination camera with a plastic and fiber optics positron emission tomography (PET) camera inside an magnetic resonance imaging (MRI) magnet. Separate development of both technologies; Incompatibility of the PET camera and with the MRI magnet; Construction of...

  • Neuroimaging Illuminates Acupuncture's Effects on the Brain.  // Shift: At the Frontiers of Consciousness;Dec2007/Jan2008, Issue 17, p39 

    The article focuses on the neuroimaging data released by Rupali P. Dhond and colleagues and published in the July/August 2007 issue of the "Journal of Alternative and Complementary Medicine." It suggests that therapeutic acupuncture such as functional magnetic resonance imaging (fMRI), positron...

  • Glutamatergic function in the resting awake human brain is supported by uniformly high oxidative energy. Hyder, Fahmeed; Fulbright, Robert K; Shulman, Robert G; Rothman, Douglas L // Journal of Cerebral Blood Flow & Metabolism;Mar2013, Vol. 33 Issue 3, p339 

    Rodent 13C magnetic resonance spectroscopy studies show that glutamatergic signaling requires high oxidative energy in the awake resting state and allowed calibration of functional magnetic resonance imaging (fMRI) signal in terms of energy relative to the resting energy. Here, we derived energy...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics