TITLE

Transmission imaging for registration of ictal and interictal single-photon emission tomography, magnetic resonance imaging and electroencephalography

AUTHOR(S)
Sipilä, Outi; Nikkinen, Päivi; Savolainen, Sauli; Granström, Marja-Liisa; Gaily, Eija; Poutanen, Veli-Pekka; Pohjonen, Hanna; Liewendahl, Kristian
PUB. DATE
February 2000
SOURCE
European Journal of Nuclear Medicine;2000, Vol. 27 Issue 2, p202
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Abstract. A method developed for registration of ictal and interictal single-photon emission tomography (SPET), magnetic resonance imaging (MRI) and electroencephalography (EEG) is described. For SPET studies, technetium-99m ethyl cysteinate dimer (ECD) was injected intravenously while the patient was monitored on video-EEG to document the ictal or interictal state. Imaging was performed using a triple-head gamma camera equipped with a transmission imaging device using a gadolinium-153 source. The images (128x128 pixels, voxel size 3.7x3.7x3.6 mm[sup 3]) were reconstructed using an iterative algorithm and postfiltered with a Wiener filter. The gold-plated silver electrodes on the patient's scalp were utilized as markers for registration of the ictal and interictal SPET images, as these metallic markers were clearly seen on the transmission images. Fitting of the marker sets was based on a non-iterative least squares method. The interictal SPET image was subtracted from the ictal image after scaling. The T1-weighted MPRAGE MR images with voxel size of 1.0x1.0x1.0 mm[sup 3] were obtained with a 1.5-T scanner. For registration of MR and subtraction SPET images, the...
ACCESSION #
4720975

 

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