TITLE

VALIDATION OF A HPLC METHOD OF DOPAMINE HYDROCHLORIDE DETERMINATION FROM INJECTABLE PREPARATIONS

AUTHOR(S)
Rosca, Cosmin; Bojiţă, Marius; Negru, Ancamaria
PUB. DATE
December 2009
SOURCE
Clujul Medical;Dec2009, Vol. 82 Issue 4, p520
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This paper introduces the validation of a HPLC UV detection method of dopamine hydrochloride (DH) determination from injectable preparations. The chromatographic analysis used a Zorbax C18 chromatographic column, 150x4.6mm, 5μm. The determined substance was detected at 280nm wave length. The calibration curve for DH was linear in the interval of concentration 12-40 μg/ml. The dosage method was validated by linearity, specificity, and accuracy.
ACCESSION #
47121789

 

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