TITLE

ETIOPATOGENEZA ESOFAGULUI BARRETT

AUTHOR(S)
Săraci, George; Oliviu Pascu
PUB. DATE
December 2009
SOURCE
Clujul Medical;Dec2009, Vol. 82 Issue 4, p463
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Barrett`s Oesophagus is an important cause of morbidity and mortality mainly through its evolution to esophageal adenocarcinoma, a fact pointed out by a 360 times higher relative risk. In most European countries, there is a rising tendency of oesophageal adenocarcinoma and a descendent one for scuamous carcinoma, therefore we are witnessing the exact opposite tendency from the one existing 30 years ago. The main cause of BE is GERD, thus any factor that produces GERD is virtually a risk factor in developing BE (food, coffee, smoking, immunopression, obesity a.o). Aditionally, a large amount of environmental, constitutional and genetic factors are involved.
ACCESSION #
47121777

 

Related Articles

  • Receipt of Previous Diagnoses and Endoscopy and Outcome From Esophageal Adenocarcinoma: A Population-Based Study With Temporal Trends. Cooper, Gregory S.; Tzyung Doug Kou; Chak, Amitabh // American Journal of Gastroenterology;Jun2009, Vol. 104 Issue 6, p1356 

    OBJECTIVES:Endoscopic screening of the at-risk population with chronic gastroesophageal reflux disease (GERD) for the presence of intestinal metaplasia or Barrett's esophagus has been suggested as a method to reduce mortality from esophageal adenocarcinoma. There are only limited data regarding...

  • Immunohistochemical assessment for Cdx2 expression in the Barrett metaplasia–dysplasia–adenocarcinoma sequence. Stephen Hayes // Journal of Clinical Pathology;Feb2011, Vol. 64 Issue 2, p110 

    BACKGROUND: Barrett oesophagus (BO) occurs as a consequence of prolonged gastro-oesophageal reflux and it may precede the development of oesophageal adenocarcinoma. AIMS: The aim of this study was to accurately assess Cdx2 expression in the oesophageal...

  • Meta-Analyses of the Effect of Symptoms of Gastroesophageal Reflux on the Risk of Barrett's Esophagus. Taylor, Justin B.; Rubenstein, Joel H. // American Journal of Gastroenterology;Aug2010, Vol. 105 Issue 8, p1730 

    OBJECTIVES:Esophageal adenocarcinoma (EAC) is a devastating disease that has risen in incidence over the past several decades. Barrett's esophagus (BE) is an associated premalignant lesion. Current preventative efforts rely on endoscopic screening of individuals with gastroesophageal reflux...

  • Barrett's Esophagus and Intestinal Metaplasia of Gastric Cardia: Prevalence, Clinical, Endoscopic and Histological Features. Pascarenco, Ofelia Daniela; Boeriu, Alina; Mocan, Simona; Pascarenco, Ghenadie; Drasoveanu, Silvia; Galeanu, Marinela; Dobru, Daniela // Journal of Gastrointestinal & Liver Diseases;Mar2014, Vol. 23 Issue 1, p19 

    Background & Aims: Over the past few decades, the incidence of adenocarcinomas of the gastroesophageal junction has rapidly increased. Barrett's esophagus is a risk factor for esophageal adenocarcinoma, but the role of intestinal metaplasia of the gastric cardia as a precursor in cardia-related...

  • Diagnostic Challenges in the Pathologic Evaluation of Barrett Esophagus. Yantiss, Rhonda K. // Archives of Pathology & Laboratory Medicine;Nov2010, Vol. 134 Issue 11, p1589 

    Context.--Barrett esophagus represents an unstable epithelium resulting from chronic gastroesophageal reflux disease. Patients with Barrett esophagus routinely undergo endoscopic examination to detect dysplasia and early carcinoma. Although appropriate classification of Barrett esophagus and...

  • Does impaired gallbladder function contribute to the development of Barrett's esophagus and esophageal adenocarcinoma? Nassr, Ayman; Gilani, Syeda; Atie, Mohammed; Abdelhafiz, Tariq; Connolly, Val; Hickey, Neil; Walsh, Thomas; Nassr, Ayman O; Gilani, Syeda Nadia Shah; Walsh, Thomas Noel // Journal of Gastrointestinal Surgery;Jun2011, Vol. 15 Issue 6, p908 

    Introduction: Esophageal adenocarcinoma is aetiologically associated with gastro-esophageal reflux, but the mechanisms responsible for the metaplasia-dysplasia sequence are unknown. Bile components are implicated. Impaired gallbladder function may contribute to duodenogastric reflux...

  • Barrett’s Esophagus, Fundoplication, and Cancer. Watson, David I.; Mayne, George C.; Hussey, Damian J. // World Journal of Surgery;Mar2007, Vol. 31 Issue 3, p447 

    The author reflects on the gastro-esophageal reflux and Barrett's esophagus. According to the author, gastro-esophageal reflux and Barrett's esophagus have become increasingly common in all Western countries, underpinning a 300-400% increase in the incidence of esophageal adenocarcinoma. The...

  • Editorial: Where Are You and How Do We Find You? The Dilemma of Identifying Barrett's Epithelium Before Adenocarcinoma of the Esophagus. Wong, Roy K. H.; Altekruse, Sean F. // American Journal of Gastroenterology;Jun2009, Vol. 104 Issue 6, p1363 

    The incidence of esophageal adenocarcinoma in white males has been increasing steadily over the past decade. However, attempts to identify the precursor lesion, intestinal metaplasia of the esophagus, or early in-situ cancers have been dismal, with no increase in the diagnosis of early cancers...

  • Molecular Abnormalities in Pediatric Barrett Esophagus: Can We Test for Potential of Neoplastic Progression? Maltby, Edna L.; Dyson, Michael J.; Wheeler, Mark R.; Thomson, Mike; Sethuraman, Chitra; Cohen, Marta C. // Pediatric & Developmental Pathology;Jul/Aug2010, Vol. 13 Issue 4, p310 

    Barrett esophagus (BE) is a preneoplastic condition that predisposes to esophageal adenocarcinoma and is a consequence of prolonged gastroesophageal reflux disease. The condition is mainly seen in adults and is thought to be a complex disease in which individual genetic predisposition interacts...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics