Cronkhite-Canada syndrome: report of two cases

Murata, Ikuo; Yoshikawa, Ichiro; Endo, Masaaki; Tai, Mayumi; Toyoda, Chii; Abe, Shintaro; Hirano, Yoshiaki; Otsuki, Makoto
September 2000
Journal of Gastroenterology;2000, Vol. 35 Issue 9, p706
Academic Journal
Abstract: Two cases of Cronkhite-Canada syndrome are reported. In the first case, a 56-year-old woman had an adenoma of the colon, arising within the Cronkhite-Canada polyps, which was removed by endoscopic polypectomy. This suggests possible neoplastic transformation of polyps in this syndrome. She achieved remission with corticosteroids, but the polyposis recurred (only in the stomach) 7 months after the remission. In the recurrent polyposis, corticosteroid therapy resulted again in complete remission, which has lasted for 5 years. In the second case, a 69-year-old man developed typical manifestations of the syndrome while under emotional stress. He had a past history of chronic pityriasis lichenoides, and serum antinuclear antibody was positive. These findings suggested a possible role of autoimmune response in the pathogenesis of the syndrome. Corticosteroids were also effective in this patient.


Related Articles

  • A Case of Double Pylorus Accompanied by Adrenal Adenoma. Yousuf, Muhammad; Kameya, Saeko; Noda, Aiji; Watanabe, Tsutomu // American Journal of Gastroenterology;Feb1989, Vol. 84 Issue 2, p173 

    We report here a case of double pylorus diagnosed endoscopically in a patient with adrenal adenoma. A 44-yr-old man was found to have double pylorus during examinations for recurrent epigastric pain and obesity. We think that the formation of double pylorus in this case resulted from recurrent...

  • An Adrenal Mass in a 54-Year-Old Man. Stephany, Joshua D.; Pearl, Gary S. // Archives of Pathology & Laboratory Medicine;Jul2003, Vol. 127 Issue 7, p883 

    Presents a case study of a 54-year-old black man with an adrenal mass who was diagnosed with adrenocortical adenoma with spironolactone bodies. Medical history of the patient; Cause of primary hyperaldosteronism; Information on spironolactone.

  • Pseudoglandular Pattern in a Myxoid Adrenocortical Adenoma. MacQuarrie, Erin; Helyer, Lucy; Merrimen, Jennifer // Canadian Journal of Pathology;2011, Vol. 3 Issue 3, p20 

    A myxoid adrenocortical adenoma with a pseudoglandular pattern is described. The distinction from metastatic adenocarcinoma is discussed.

  • Significance of heparanase-1 and vascular endothelial growth factor in adrenocortical carcinoma angiogenesis: potential for therapy. Xu, Yun-ze; Zhu, Yu; Shen, Zhou-jun; Sheng, Jia-yan; He, Hong-chao; Ma, Gui; Qi, Yi-cheng; Zhao, Ju-ping; Wu, Yu-xuan; Rui, Wen-bin; Wei, Qing; Zhou, Wen-long; Xie, Xin; Ning, Guang // Endocrine (1355008X);Dec2011, Vol. 40 Issue 3, p445 

    The purpose of this study was to determine the correlation between human adrenocortical carcinoma (ACC) and the proteins involved in tumor angiogenesis, and to evaluate the angiogenic status of ACC. The expression of heparanase-1 (HPA-1), vascular endothelial growth factor (VEGF), and vascular...

  • Primary aldosteronism due to adrenocortical adenoma with concurrent ileum carcinoid tumor: case report. Zinnamosca, L.; Petramala, L.; Cotesta, D.; Marinelli, C.; Sciomer, S.; Cavallaro, G.; Ciardi, A.; Massa, R.; Toma, G.; Filetti, S.; Letizia, C. // Endocrine (1355008X);Dec2010, Vol. 38 Issue 3, p313 

    Primary aldosteronism (PA) with synchronous carcinoid syndrome is extremely rare occurrence. In this article, we describe a case of PA due to adrenocortical adenoma ('aldosteronoma') and concurrent malignant carcinoid tumor of ileum. The patient was treated with synchronous right adrenalectomy...

  • Adrenocortical Adenoma and Carcinoma: Histopathological and Molecular Comparative Analysis. Stojadinovic, Alexander; Brennan, Murray F.; Hoos, Axel; Omeroglu, Atilla; Leung, Denis H. Y.; Dudas, Maria E.; Nissan, Aviram; Cordon-Cardo, Carlos; Ghossein, Ronald A. // Modern Pathology;Aug2003, Vol. 16 Issue 8, p742 

    We compared histomorphological features and molecular expression profiles of adrenocortical adenomas (ACAd) and carcinomas (ACCa). A critical histopathological review (mean, 11 slides per patient) was conducted of 37 ACAd and 67 ACCa. Paraffinembedded tissue cores of ACAd (n = 33) and ACCa (n =...

  • Early Palliation of Oculomotor Nerve Palsy following Gamma Knife Radiosurgery for Pituitary Adenoma. Abe, Takumi; Yamamoto, Masaaki; Taniyama, Matsuo; Tanioka, Daisuke; Izumiyama, Hitoshi; Matsumoto, Kiyoshi // European Neurology;2002, Vol. 47 Issue 1, p61 

    Provides information on a medical case on isolated oculomotor nerve palsy following gamma knife radiosurgery for pituitary adenoma. Regrowth of an adrenocorticotropic hormone; Findings of a neurological examination; Factors that lead to the improvement of the oculomotor nerve palsy.

  • Lower expression of ATM and gene deletion is more frequent in adrenocortical carcinomas than adrenocortical adenomas. Ye, Junna; Qi, Yan; Wang, Weiqing; Sun, Fukang; Wei, Qin; Su, Tingwei; Zhou, Weiwei; Jiang, Yiran; Yuan, Wenqi; Cai, Jianfei; Cui, Bin; Ning, Guang // Endocrine (1355008X);Jun2012, Vol. 41 Issue 3, p479 

    Adrenocortical carcinoma (ACC) is a rare endocrine malignancy accounting for approximately 0.02-0.2% of all cancer deaths. The molecular pathogenesis of ACC has been the hot topic of recent reviews but it is still poorly understood. It is imperative to have a better understanding on the...

  • What's Hot in the Red Journal This Month.  // American Journal of Gastroenterology;Nov2014, Vol. 109 Issue 11, p1695 

    A preview of articles from the November 2014 issue is presented, which include "Antibiotics Associated With Increased Risk of New-Onset Crohn's Disease But Not Ulcerative Colitis: A Meta-Analysis";"What Level of Bowel Prep Quality Requires Early Repeat Colonoscopy: Systematic Review and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics