TITLE

Primary hyperoxaluria 1: catch up growth and normalization of oxaluria 6 years after hepatorenal transplantation in a prepubertal boy

AUTHOR(S)
Walden, U.; Böswald, M.; Dörr, H. G.; Ruder, H.
PUB. DATE
September 1999
SOURCE
European Journal of Pediatrics;1999, Vol. 158 Issue 9, p727
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Abstract We present data on urinary oxalate (U[sub ox]), renal function, growth and bone age in a 10-year-old male with primary hyperoxaluria type 1. The patient had undergone combined liver-kidney transplantation at the age of 4.5 years. U[sub ox] increased up to 10[sup 4] micro mol/24 h after transplantation and declined to normal values thereafter. Excessive U[sub ox] concentrations after surgery might have been due to a bone pool of unsoluble oxalate and declined spontaneously. Creatinine clearance remained stable during observation period. The boy showed significant catch up growth. Height standard deviation score for chronological age improved from -2.4 before transplantation to -0.3 after 6 years. Radiological bone density improved at the same time.
ACCESSION #
4677911

 

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