TITLE

Mechanism of oxidative stress generation in cells by localized near-infrared femtosecond laser excitation

AUTHOR(S)
Hao He; Kam Tai Chan; Siu Kai Kong; Lee, Rebecca Kit Ying
PUB. DATE
December 2009
SOURCE
Applied Physics Letters;12/7/2009, Vol. 95 Issue 23, p233702
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We examined the effect of femtosecond (fs) and continuous wave (CW) lasers at near-infrared range on the creation of reactive oxygen species in a human liver cancer cell line. By controlling the mitochondria electron transport chain (ETC), it was found that a major part of the oxidative stress was generated by the laser induced thermal effect on the mitochondria while the remaining part was created by direct free electron liberation by the fs pulses, which could be observed after breaking the ETC. The study helps clarify the major effects produced on animal cells when excited by fs lasers.
ACCESSION #
46708306

 

Related Articles

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics