TITLE

2009 - Review: PPI use in pregnancy was not associated with increased congenital malformations, spontaneous abortion, or preterm delivery

AUTHOR(S)
Bharucha, Adil E.; Koren, G.
PUB. DATE
November 2009
SOURCE
ACP Journal Club;11/17/2009, Vol. 151 Issue 5, p12
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a study which examines the safety of proton-pump inhibitors (PPIs) taken during early pregnancy and its effects on the fetus. PPIs are used to treat reflux and omeprazole increases embryonic and fetal mortality in animals. However, no evidence was found to show that the use of PPIs during the first trimester of pregnancy results in increased risk for congenital malformations, spontaneous abortion, or preterm delivery.
ACCESSION #
45665932

 

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