2009 - Review: PPI use in pregnancy was not associated with increased congenital malformations, spontaneous abortion, or preterm delivery
- PPI use during early pregnancy appears safe. // Reactions Weekly;12/11/2010, Issue 1331, p2
The article discusses research being done on the application of proton-pump inhibitors (PPIs) in early pregnancy and its association with the risk of birth defects. It references a study by BjÃ¶rn Pasternak and colleagues in the November 2010 issue of the "New England Journal of Medicine." For...
- omeprazole. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1628
A definition of the term "omeprazole" which refers to an inhibitor of the gastric acid formation is presented.
- DIFFERENCES IN PPIs. Schwartz, Steven // Clinical Advisor;Feb2010, Vol. 13 Issue 2, p76
The article provides an answer to a question on the cost and effectiveness of omeprazole and proton pump inhibitors (PPIs).
- Tissue Sampling Technique Affects Accuracy of Karyotype from Missed Abortions. Lathi, Ruth B.; Milki, Amin B. // Journal of Assisted Reproduction & Genetics;Nov2002, Vol. 19 Issue 11, p536
Determines if careful specimen selection and washing of tissue from first trimester missed abortion products of conception specimens increases the sensitivity of routine cytogenetics in detecting aneuploidy. Percentage of 46XX results decreased in the test group when compared to historical and...
- Long-term PPI therapy safe. // Reactions Weekly;May2015, Vol. 1553 Issue 1, p7
The article focuses on a study which shows that long-term treatment with the proton pump inhibitors omeprazole and esomeprazole is not linked with any safety concern.
- Proton-Pump Inhibitors and Birth Defects ï¿½ Some Reassurance, but More Needed. Mitchell, Allen A. // New England Journal of Medicine;11/25/2010, Vol. 363 Issue 22, p2161
The author reflects on the effect of the use of proton-pump inhibitors (PPIs) during pregnancy on the occurrence of birth defects. It presents the study conducted in Denmark, which showed that the use of PPIs like omeprazole, lansoprazole and esomeprazole has no major effect on the possibility...
- Valproic acid use in pregnancy ups risk of malformations. // Reactions Weekly;7/10/2010, Issue 1309, p2
The article discusses a study which found that valproic acid monotherapy during the first trimester of pregnancy could increase the risk of congenital malformations in the offspring of the pregnant women.
- Drug points. Bong, J L; Lucke, T W; Douglas, W S // BMJ: British Medical Journal (International Edition);01/29/2000, Vol. 320 Issue 7230, p283
Offers a look on a case of lichenoid eruption in reaction to proton pump inhibitors. Clinical manifestations of the skin disease; Mechanism of action of the inhibitor; Adverse effects of omeprazole.
- Drug Interaction Studies with Esomeprazole, the (S)-Isomer of Omeprazole. Andersson, T.; Hassan-Alin, M.; Hasselgren, G.; Röhss, K. // Clinical Pharmacokinetics;2001, Vol. 40 Issue 7, p523
Esomeprazole, the (S)-isomer of omeprazole, is the first proton pump inhibitor (PPI) developed as a single isomer for the treatment of patients with acid related diseases. Because of the extensive use of PPIs, the documentation of the potential for drug interactions with esomeprazole is of great...