2009 - Percutaneous closure of the left atrial appendage was noninferior to warfarin in atrial fibrillation

Sobieraj-Teague, Magdalena; Eikelboom, John; Holmes, D. R.
November 2009
ACP Journal Club;11/17/2009, Vol. 151 Issue 5, p8
Academic Journal
The article presents information about a clinical trial which analyzes whether percutaneous closure of the left atrial appendage (LAA) in patients with nonvalvular atrial fibrillation, is equal to warfarin for preventing stroke. The study involved 707 patients of 18 years of age. The results show that warfarin was as effective as percutaneous closure of the left atrial appendage for preventing stroke but it also increased adverse effects.


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