Matusevičius, Algimantas; Grigonis, Aidas; Noreika, Algis; Zamokas, Gintaras; Kybartas, Modestas
September 2009
Veterinarija ir Zootechnika;2009, Vol. 47 Issue 69, p66
Academic Journal
Carbasept and Carbasept-oxy creams were created for treatment of wounds and inflammations. They are made from emulsion-type base (water, oil) with urea, methyl salycilate, camphor, and oxytetracycline was added to oxy-oinment. Investigations revealed that using carbasept fresh wounds in dogs healed in 9,1±1,61 days and in cats 5,2 ±1,47 days. Treatment of contaminated, purulent wounds took longer - 17,1±1,72 days in dogs and 10,1±1,65 days in cats. Using carbasept-oxy fresh wounds healed faster, compared to carbasept (5-8 and 4-6 days respectively), and purulent wounds healed in 10-13 days in dogs and in 7-10 days in cats. Fresh wounds in horses and cattle treated with carbasept healed in 15,6±5,51 and 8,1±1,94 days, respectively. Treatment of contaminated purulent wounds took longer, in horses up to 26 days, in cattle up to 19 days. Using carbasept-oxy the duration of treatment was shorter, compared to carbasept. Purulent wounds in horses healed in 10-20 (average 12,2±3,53) days, in cattle in 6-9 (average7,3±1,52) days. Tendinitis in horses healed in 6-14 (average 11,2±3,12) days. Purulent tendinitis due to wound healed in 18-29 days. Commotion of the joint healed in 14-23 days (average 18,5±3,14) days. We have to admit that the emulsion-type base that we made and medications that are present in the creams add to one another's action, shows good activity in inflamed tissues, and carbasept stimulates transdermal penetration of medications and retraction of exudate from inflammed tissues. Carbasepts demonstrate antimicrobic and antiinflammatory activity, are effective in treatment of purulent wounds, help to remove toxins, dead tissues and contaminants from the inflammation site. It's suggested to use carbasept to treat wounds, tendinitis and periartritis.


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