TITLE

Recent advances in coeliac disease genetics

AUTHOR(S)
Hunt, Karen A.; van Heel, David A.
PUB. DATE
April 2009
SOURCE
Gut;Apr2009, Vol. 58 Issue 4, p473
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article offers information on coeliac disease, which affects around one in 100 individuals in Europe. The disease generates an immune response in the small intestine to fragments of gluten leading to architectural changes in the small intestine which include villous atrophy and an increase in the number of intra-epithelial cells. It mentions the inherited genetic factors affecting the disease aside from the well known environmental factor, the gluten.
ACCESSION #
45646914

 

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