TITLE

Clinical trial for Fabry disease faces continuing hurdles

AUTHOR(S)
Silversides, Ann
PUB. DATE
November 2009
SOURCE
CMAJ: Canadian Medical Association Journal;11/24/2009, Vol. 181 Issue 11, pE251
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article informs that the clinical trial for Fabry disease conducted by the Canadian Fabry Disease Initiative is facing problems because of the worldwide shortage of one of the enzyme replacement therapies. It is stated that the trial involves a comparison of the agalsidase beta (Fabrazyme) and agasidase alfa (Replegal), but the global shortage of agalsidase beta has created new challenges like reducing dose of Fabrazyme to patients and threatening the integrity of the post market trial.
ACCESSION #
45520301

 

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