Locally Delivered Bisphosphonate for Enhancement of Bone Formation and Implant Fixation

Bobyn, J. Dennis; McKenzie, Kimberly; Karabasz, Dorota; Krygier, Jan J.; Tanzer, Michael
November 2009
Journal of Bone & Joint Surgery, American Volume;Nov2009 Supplement 6, Vol. 91-A, p23
Academic Journal
The article discusses the study of the quantifiable effect of local delivery of different doses of zoledronic acid on bone growth within and about porous tantalum implants put in for one year. The improved net local bone formation is explained by the study. Tables of extent of bone ingrowth, apposition and filling of medullary canal with per-implant bone are also offered.


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