Applied public health research - falling through the cracks?

Simmons, Rebecca K.; Ogilvie, David; Griffin, Simon J.; Sargeant, Lincoln A.
January 2009
BMC Public Health;2009, Vol. 9 Issue 1, p362
Academic Journal
Background: There is a degree of dissonance between the types of evaluative research required by organisations providing or commissioning health care, those recommended by organisations developing evidence-based guidance, and those which research funding bodies are prepared to support. Methods: We present a case study of efforts to establish a pragmatic but robust evaluation of local exercise referral schemes. We considered the epidemiological, ethical and practical advantages and disadvantages of a number of study designs and applied for research funding based on an uncontrolled design, outlining the difficulties of carrying out a randomised controlled trial to evaluate an existing service. Results: Our proposal was praised for its relevance and clear patient outcomes, but the application was twice rejected because both funders and reviewers insisted on a randomised controlled trial design, which we had found to be impractical, unacceptable to service users and potentially unethical. Conclusion: The case study highlights continuing challenges for applied public health research in the current funding climate.


Related Articles

  • Bringing more life-saving clinical trials to Westchester. HOPKINS, UNA // Westchester County Business Journal;9/1/2014, Vol. 50 Issue 35, p15 

    The article discusses the role of clinical trials as a component of a comprehensive cancer care program in Westchester County, New York. It highlights the case of patients involved in clinical trials at White Plains Hospital, citing the health and psychological benefit of patients from clinical...

  • Ethics and Scientific Integrity in Public Health, Epidemiological and Clinical Research. Coughlin, Steven S.; Barker, Amyre; Dawson, Angus // Public Health Reviews (2107-6952);2012, Vol. 34 Issue 1, p1 

    The ethics and scientific integrity of biomedical and public health research requires that researchers behave in appropriate ways. However, this requires more than following of published research guidelines that seek to prevent scientific misconduct relating to serious deviations from widely...

  • Association between competing interests and authors' conclusions: epidemiological study of randomised clinical trials published in the BMJ. Kjaergard, Lise L; Als-Nielsen, Bodil // BMJ: British Medical Journal (International Edition);8/3/2002, Vol. 325 Issue 7358, p249 

    Abstract Objective: To assess the association between competing interests and authors' conclusions in randomised clinical trials. Design: Epidemiological study of randomised clinical trials published in the BMJ from January 1997 to June 2001. Financial competing interests were defined as funding...

  • Assuring Adequate Protections in International Health Research: A Principled Justification and Practical Recommendations for the Role of Community Oversight. Buchanan, David; Sifunda, Sibusiso; Naidoo, Nasheen; James, Shamagonam; Reddy, Priscilla // Public Health Ethics;Nov2008, Vol. 1 Issue 3, p246 

    The analysis presented here lays out the ethical warrants for requiring community oversight of health research conducted in international settings. It reviews the inadequacies with the current standards of individual informed consent and research ethics committee review, and then, shows how a...

  • Using the Revised Diagnostic Criteria for Frontotemporal Dementia in India: Evidence of an Advanced and Florid Disease. Ghosh, Amitabha; Dutt, Aparna; Ghosh, Madhura; Bhargava, Pallavi; Rao, Sulakshana // PLoS ONE;Apr2013, Vol. 8 Issue 4, p1 

    Background: The International Consortium (FTDC) that revised the diagnostic criteria for behavioural variant frontotemporal dementia (bvFTD) did not have an Asian representation. Whether the revised criteria are equally useful in the early detection of Asian bvFTD patients therefore remains...

  • Revisiting the Belmont Report: The Ethical Significance of the Distinction between Clinical Research and Medical Care. Miller, Franklin G. // APA Newsletters;Fall2005, Vol. 5 Issue 1, p10 

    The article discusses the ethical significance of distinguishing between the activities of clinical research and medical care in the "Belmont Report." It states that medical care entails experimentation in the process of developing treatments for patients and adjusting them to maximize the...

  • Assessing the quality of informed consent in a resource-limited setting: A cross-sectional study. Kiguba, Ronald; Kutyabami, Paul; Kiwuwa, Stephen; Katabira, Elly; Sewankambo, Nelson K. // BMC Medical Ethics;2012, Vol. 13 Issue 1, p21 

    Background: The process of obtaining informed consent continues to be a contentious issue in clinical and public health research carried out in resource-limited settings. We sought to evaluate this process among human research participants in randomly selected active research studies approved by...

  • India mulling stricter laws to curb unethical trials. Jayaraman, Killugudi // Nature Medicine;Feb2012, Vol. 18 Issue 2, p182 

    The article focuses on the efforts of the government in developing ethical clinical trial practices in India. The initiative was due to a series of revelations about instances of unethical clinical trial practices in the country, in which the Indian Department of Health Research addressed...

  • A comparison of justice frameworks for international research. Pratt, Bridget; Loff, Bebe // Journal of Medical Ethics;Jul2015, Vol. 41 Issue 7, p539 

    Justice frameworks have been developed for international research that provide guidance on the selection of research targets, ancillary care, research capacity strengthening, and post-trial benefits. Yet there has been limited comparison of the different frameworks. This paper examines the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics