Alcohol consumption and carotid artery structure in Korean adults aged 50 years and older

Young-Hoon Lee; Min-Ho Shin; Sun-Seog Kweon; Sung-Woo Choi; Hye- Yeon Kim; So-Yeon Ryu; Bok-Hee Kim; Jung-Ae Rhee; Jin-Su Choi
January 2009
BMC Public Health;2009, Vol. 9 Issue 1, p358
Academic Journal
Background: Epidemiologic studies of the association between alcohol consumption and carotid artery structure have reported conflicting results. We investigated the association between alcohol consumption and carotid atherosclerosis by evaluating the effects of alcohol intake on carotid artery enlargement. Methods: The study population consisted of 4302 community-dwelling Koreans (1577 men and 2725 women) aged 50 years and over. All the subjects had participated in the baseline survey of the Dong-gu Study conducted between 2007 and 2008. Daily alcohol consumption was determined by the number and frequency of alcoholic beverages consumed. We measured common carotid artery intima-media thickness (CCA-IMT), common carotid and bulb IMT (CB-IMT), carotid plaques, and the diameter of the common carotid artery (CCA-diameter) using high-resolution B-mode ultrasonography. We used analysis of covariance and multiple logistic regressions to determine the relationship between alcohol consumption and carotid artery parameters. Results: CCA-IMT and CB-IMT were negatively correlated with alcohol consumption after controlling for cardiovascular risk factors in men (p for linear trend = 0.009 and = 0.038, respectively). The multivariate-adjusted odds ratio (OR) for carotid plaques was significantly higher in men who consumed >40.0 g/d (OR = 1.81, 95% CI = 1.13-2.91), although a significant positive correlation was observed between alcohol consumption and carotid plaques (p for linear trend = 0.027). Neither carotid IMT nor carotid plaques were correlated with alcohol intake in women. Alcohol intake was positively correlated with CCA-diameter adjusted for carotid IMT and plaques in the multivariate-adjusted model in both sexes (p for linear trend <0.001 for men and 0.020 for women). Conclusion: The results of our study indicate that alcohol consumption is inversely related to carotid IMT and positively related to carotid plaques in men, but not women. However, alcohol intake is positively associated with CCA-diameter in both men and women. Additional large population-based prospective studies are needed to confirm the effects of alcohol consumption on carotid artery structure.


Related Articles

  • Moyamoya disease. Serratos, Felipe Farias; Ishikawa, Tatsuya; Yoshida, Yasuji; Moroi, Junta; Sawada, Motoshi; Kobayashi, Norikata; Mutoh, Tatsushi; Jun, Ren; Serratos, Claudia V. Farias // Archivos de Neurociencias;ene-mar2009, Vol. 14 Issue 1, p33 

    Moyamoya disease (MMD) was reported by first time in 1957 by Takeuchi and Shimizu as hypoplasia of the bilateral internal carotid arteries. The official Japanese name for the disease is Spontaneous occlusion of the circle of Willis, but in 1967 Suzuki and Aka nicknamed it Moyamoya disease. In...

  • The correlation between the severity of peripheral arterial disease and carotid occlusive disease. Long, T.H.; Criqui, M.H.; O Denenberg, J.; Vasilevskis, E.E.; Klauber, M.R.; Fronek, A. // Vascular Medicine;1999, Vol. 4 Issue 3, p135 

    Peripheral arterial disease (PAD) and carotid occlusive disease (COD) are both known to be specific manifestations of atherosclerosis. Because they both have a common cause, it is reasonable to hypothesize that they should correlate with each other to a certain extent, and previous studies have...

  • Total serum homocysteine – a predictor of extracranial carotid artery stenosis in male patients with symptomatic peripheral arterial disease. Mueller, T.; Furtmueller, B.; Aigelsdorfer, J.; Luft, C.; Poelz, W.; Haltmayer, M. // Vascular Medicine;2001, Vol. 6 Issue 3, p163 

    High total serum homocysteine (tHcy) concentrations are associated with an increased risk of carotid artery disease in the general population. Since patients with peripheral arterial disease (PAD) have a threefold risk of cerebrovascular morbidity compared to individuals free of PAD, and since...

  • Airway Obstruction Secondary to Extracranial Carotid-Artery Pseudoaneurism. White, John A.; MacRae, Duncan // Journal of Otolaryngology;Mar/Apr1999, Vol. 28 Issue 2, p105 

    Presents the case of a patient with an extracranial pseudoanuerysm of the left common carotid artery that presented without any history of trauma. Disease onset; Relevant medical history; Presence of a left mandibular swelling that extended to the superior border of the left clavicle; Excavation...

  • Course of stroke in internal carotid artery dissection is unpredictable.  // Modern Medicine;Aug95, Vol. 63 Issue 8, p45 

    Presents an abstract of the study titled `Time course of symptoms in extracranial carotid artery dissectors: A series of 80 patients,' by V. Biousse, J. D'Anglejan-Chatillon, et al, published in the February 1995 issue of `Stroke'.

  • Lipid-lowering therapy slows progression of atherosclerosis in carotid arteries.  // Modern Medicine;Jul96, Vol. 64 Issue 7, p51 

    Presents an abstract on the article `Reduction in Carotid Arterial Wall Thickness Using Lovastatin and Dietary Therapy: A Randomized, Controlled Clinical Trial,' by H.N. Hodis, W.J. Mack et al published in the March 15, 1996 issue of the `Internal Medicine' journal.

  • Prospective Evaluation of Hypertensive Patients with Carotid Kinking and Coiling. Oliviera, Ugo; Scherillo, Giovanna; Casaburi, Cosma; Di Martino, Marilena; Di Gianni, Angela; Serpico, Raffaella; Fazio, Serafino; Saccà, Luigi // Angiology;Mar/Apr2003, Vol. 54 Issue 2, p169 

    The aim of this study was to determine the incidence of vascular events during a 7-year followup evaluation in a group of 34 hypertensive patients with kinking of the internal carotid artery and 36 well-matched hypertensive control subjects. The carotid intima-media thickness (IMT) was measured...

  • Who can benefit from carotid endarterectomy?  // Patient Care;11/30/1997, Vol. 31 Issue 19, p58 

    Presents information relating to carotid endarterectomies (CEAs). Statistics on the increase of CEAs performed in the United States; What this increase is attributed to; Requirements for selecting candidates for carotid endarterectomy; Details on the assessment of stroke risk. INSETS: Carotid...

  • Is routine carotid screening for coronary surgery needed? Walker, William A.; Harvey, William R. // American Surgeon;Apr1996, Vol. 62 Issue 4, p308 

    Investigates the hypothesis that clinical criteria alone can be used for deciding when preoperative carotid artery screening is needed. Link between carotid and coronary artery disease; Symptoms; Risk factors including history of ischemic attack or stroke.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics