TITLE

Salivary cotinine concentrations in daily smokers in Barcelona, Spain: a cross-sectional study

AUTHOR(S)
Fu, Marcela; Fernandez, Esteve; Martínez-Sánchez, Jose M.; Pascual, José A.; Schiaffino, Anna; Agudo, Antoni; Ariza, Carles; Borràs, Josep M.; Samet, Jonathan M.
PUB. DATE
January 2009
SOURCE
BMC Public Health;2009, Vol. 9, p320
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Characterizing and comparing the determinant of cotinine concentrations in different populations should facilitate a better understanding of smoking patterns and addiction. This study describes and characterizes determinants of salivary cotinine concentration in a sample of Spanish adult daily smoker men and women. Methods: A cross-sectional study was carried out between March 2004 and December 2005 in a representative sample of 1245 people from the general population of Barcelona, Spain. A standard questionnaire was used to gather information on active tobacco smoking and passive exposure, and a saliva specimen was obtained to determine salivary cotinine concentration. Two hundred and eleven adult smokers (>16 years old) with complete data were included in the analysis. Determinants of cotinine concentrations were assessed using linear regression models. Results: Salivary cotinine concentration was associated with the reported number of cigarettes smoked in the previous 24 hours (R² = 0.339; p < 0.05). The inclusion of a quadratic component for number of cigarettes smoked in the regression analyses resulted in an improvement of the fit (R² = 0.386; p < 0.05). Cotinine concentration differed significantly by sex, with men having higher levels. Conclusion: This study shows that salivary cotinine concentration is significantly associated with the number of cigarettes smoked and sex, but not with other smoking-related variables.
ACCESSION #
45197416

 

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