Diagnosis and Treatment of Viral Myocarditis

Schultz, Jason C.; Hilliard, Anthony A.; Cooper Jr., Leslie T.; Rihal, Charanjit S.
November 2009
Mayo Clinic Proceedings;Nov2009, Vol. 84 Issue 11, p1001
Academic Journal
Myocarditis, an inflammatory disease of heart muscle, Is an Important cause of dilated cardiomyopathy worldwide. Viral infection is also an important cause of myocarditis, and the spectrum of viruses known to cause myocarditis has changed in the past 2 decades. Several new diagnostic methods, such as cardiac magnetic resonance imaging, are useful for diagnosing myocarditis. Endomyocardial biopsy may be used for patients with acute dilated cardiomyopathy associated with hemodynamic compromise, those with life-threatening arrhythmia, and those whose condition does not respond to conventional supportive therapy. important prognostic variables include the degree of left and right ventricular dysfunction, heart block, and specific histopathological forms of myocarditis. We review diagnostic and therapeutic strategies for the treatment of viral myocarditis. English-language publications in PubMed and references from relevant articles published between January 1, 1985, and August 5, 2008, were analyzed. Main keywords searched were myocarditis, dilated cardiomyopathy, endomyocardial biopsy, cardiac magnetic resonance Imaging, and Immunotherapy.


Related Articles

  • Anti-NMDA-receptor encephalitis: A review. BRENTON, J. NICHOLAS; SCHWARTZ, RICHARD H.; MADOO, LAURA // Contemporary Pediatrics;Jul2015, Vol. 32 Issue 7, p14 

    The article offers information on anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis. Topics covered include how the condition is often mistaken for viral infection, a multidisciplinary approach to comprehensive care, and the importance of the early recognition of the complex signs of the...

  • Relation between myocardial edema and myocardial mass during the acute and convalescent phase of myocarditis -- a CMR study. Zagrosek, Anja; Wassmuth, Ralf; Abdel-Aty, Hassan; Rudolph, André; Dietz, Rainer; Schulz-Menger, Jeanette // Journal of Cardiovascular Magnetic Resonance (BioMed Central);2008, Vol. 10, p1 

    Background: Myocardial edema is a substantial feature of the inflammatory response in human myocarditis. The relation between myocardial edema and myocardial mass in the course of healing myocarditis has not been systematically investigated. We hypothesised that the resolution of myocardial...

  • Acute myocarditis in a rat model: late gadolinium enhancement with histopathological correlation. Korkusuz, Huedayi; Esters, Philip; Naguib, Nagy; Nour Eldin, N.-E.; Lindemayr, Sebastian; Huebner, Frank; Koujan, Ahmed; Bug, Reinhold; Ackermann, Hanns; Vogl, Thomas J. // European Radiology;Nov2009, Vol. 19 Issue 11, p2672 

    The aim of the current study was to use an established animal model of autoimmune myocarditis and to judge the ability of cardiovascular MRI (CMR) in quantitatively measuring the extent of myocardial involvement compared with histopathological measurement of severity and extent. Experimental...

  • Time course of eosinophilic myocarditis visualized by CMR. Debl, Kurt; Djavidani, Behrus; Buchner, Stefan; Poschenrieder, Florian; Heinicke, Norbert; Feuerbach, Stefan; Riegger, Günter; Luchner, Andreas // Journal of Cardiovascular Magnetic Resonance (BioMed Central);2008, Vol. 10, p1 

    We report the diagnostic potential of cardiovascular magnetic resonance (CMR) to visualize the time course of eosinophilic myocarditis upon successful treatment. A 50-year-old man was admitted with a progressive heart failure. Endomyocardial biopsies were taken from the left ventricle because of...

  • What can cardiac magnetic resonance do for cardiologists in China? Rui Xia; Fabao Gao; Yucheng Chen; Chunhua Wang; Bing Zhang // Pakistan Journal of Medical Sciences;Sep-Oct2013, Vol. 29 Issue 5, p1290 

    A letter to the editor is presented on topic related to the use of cardiovascular magnetic resonance (CMR) technique for the diagnosis of myocardial diseases in China.

  • The prevalence and prognostic significance of right ventricular systolic dysfunction in patients with idiopathic dilated cardiomyopathy. Manolis, G.; Gulati, A.; Prasad, S. // International Journal of Students' Research;Sep2011, Vol. 1 Issue 3, p90 

    Introduction Although left ventricular (LV) volumes and ejection fraction (EF) are powerful predictors of outcome in dilated cardiomyopathy (DCM), there is limited data regarding the significance of right ventricular (RV) systolic dysfunction. Cardiovascular Magnetic Resonance (CMR) imaging is...

  • INHERITED CARDIOMYOPATHIES. Ripley, David P.; Bellenger, Nick G. // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;12/17/2011, Vol. 343 Issue 7836, p1258 

    A letter to the editor is presented commenting a study in which the authors did not elaborate the established role of cardiac magnetic resonance imaging in their clinical review of inherited cardiomyopathies.

  • Prevention of Cardiomyopathy in Transfusion-Dependent Homozygous Thalassaemia Today and the Role of Cardiac Magnetic Resonance Imaging. Aessopos, Athanassios; Berdoukas, Vasilios; Tsironi, Maria // Advances in Hematology;2009, Vol. 2009, p1 

    Transfusion and iron chelation therapy revolutionised survival and reduced morbidity in patients with transfusion-dependent beta thalassaemia major. Despite these improvements, cardiac disease remained the most common cause of death in those patients. Recently the ability to determine the degree...

  • Early detection of tumour immune-rejection using magnetic resonance imaging. Hu, D-E; Beauregard, D A; Bearchell, M C; Thomsen, L L; Brindle, K M // British Journal of Cancer;4/7/2003, Vol. 88 Issue 7, p1135 

    Dynamic contrast agent-enhanced magnetic resonance imaging measurements of the perfusion of an immunogenic murine tumour showed that immune rejection was preceded by an increase in the apparent vascular volume of the tumour. This increase in vascularity, which has been observed previously in...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics