A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos

Iwata, Tomoko
July 2000
Human Molecular Genetics;Jul2000, Vol. 9 Issue 11, p1603
Academic Journal
Studies the effect of mutation in FGFR3 on growth plate chondrocytes in embryos. Generation of the first mouse model of fibroblast growth factor receptor 3 with the K644E mutation; Embryonic onset of a neonatal lethal dwafism.


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