Dissociation of Thyrotropin and Leptin Secretion in Acute Surgical Stress in Severely Obese Patients

Michalaki, Marina; Vagenakis, Apostolos G.; Argentou, Marianna; Mylonas, Panagiotis; Kalfarentzos, Fotis; Kyriazopoulou, Venetsana
October 2009
Obesity Surgery;Oct2009, Vol. 19 Issue 10, p1424
Academic Journal
The article discusses a study that investigated the secretion of leptin and thyrotropin (TSH) and their probable interaction during the acute stress induced by bariatric surgery on 18 severely obese men. Results revealed that TSH increased during the first hour of surgery after skin incision and decreased gradually throughout the observation period. The leptin level remained unaltered, then decreased and reached a nadir at 4 hours after skin incision. The study suggests that TSH and leptin secretion are asynchronous during surgical acute stress.


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