TITLE

Cerium oxide-chitosan based nanobiocomposite for food borne mycotoxin detection

AUTHOR(S)
Kaushik, Ajeet; Solanki, Pratima R.; Pandey, M. K.; Ahmad, Sharif; Malhotra, Bansi D.
PUB. DATE
October 2009
SOURCE
Applied Physics Letters;10/26/2009, Vol. 95 Issue 17, p173703
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Cerium oxide nanoparticles (NanoCeO2) and chitosan (CH) based nanobiocomposite film deposited onto indium-tin-oxide coated glass substrate has been used to coimmobilize rabbit immunoglobin (r-IgGs) and bovine serum albumin (BSA) for food borne mycotoxin [ochratoxin-A (OTA)] detection. Electrochemical studies reveal that presence of NanoCeO2 increases effective electro-active surface area of CH-NanoCeO2/indium tin oxide (ITO) nanobiocomposite resulting in high loading of r-IgGs. BSA/r-IgGs/CH-NanoCeO2/ITO immunoelectrode exhibits improved linearity (0.25–6.0 ng/dl), detection limit (0.25 ng/dl), response time (25 s), sensitivity (18 μA/ng dl-1 cm-2), and regression coefficient (r2∼0.997).
ACCESSION #
44909818

 

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