TITLE

Assessment of the quality of life in endoscopically treated patients with mechanical jaundice, pancreatic pain and exacerbations of acute pancreatitis

AUTHOR(S)
Wierzbowski, Jacek; Majkowicz, Mikołaj; Pieńkowska, Joanna; Guzek, Marek; Smoczyński, Marian
PUB. DATE
May 2009
SOURCE
Gastroenterologia Polska / Gastroenterology;2009, Vol. 16 Issue 3, p223
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Introduction: Dynamic advances in therapeutic methods have broadened the range of indications for endoscopic therapy of diseases which have been reserved (so far) for surgical or symptomatic treatment. The quality of life is the best indicator of the efficacy and quality of therapeutic activities undertaken towards a patient. Aim of the study: Assessment of the effect of endoscopic treatment of bile ducts and pancreatic disorders on patients' general quality of life in its various aspects. Material and methods: 55 patients have took a part in the research. They were put into four subgroups: with diagnosed choledocholithiasis, bile ducts neoplasms, organized pancreatic necrosis and chronic pancreatitis. The treatment included endoscopic sphincterotomy, bile ducts and pancreatic stents placement and active transpapillary and transmural drainage. The instruments applied to measure the quality of life included: questionnaires of the European Organization for Research and Treatment of Cancer (EORTC) - QLQ-C30 and QLQ-PAN26, Hospital Anxiety and Depression Scale (HADS-M) and Cantril Ladder. Results: Analysis of the general assessment of the health condition and the quality of life revealed a difference between the results for particular diagnoses. In the group with bile ducts neoplasms, no change of the investigated parameter was observed, while the biggest difference was seen in the patients with choledocholithiasis. Endotherapy considerably lowered the anxiety in the group of the patients with choledocholithiasis and pancreatic necrosis. In all the investigated groups, the patients reported less severe pain. Conclusions: Endoscopic treatment of choledocholithiasis improves patients' general quality of life, while it has no such effect in patients with neoplastic stenosis of the bile ducts. The most visible increase in all the functional scales and in the majority of scales describing symptoms was seen in the patients with choledocholithiasis.
ACCESSION #
44833893

 

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