Assessment of the quality of life in endoscopically treated patients with mechanical jaundice, pancreatic pain and exacerbations of acute pancreatitis

Wierzbowski, Jacek; Majkowicz, Mikołaj; Pieńkowska, Joanna; Guzek, Marek; Smoczyński, Marian
May 2009
Gastroenterologia Polska / Gastroenterology;2009, Vol. 16 Issue 3, p223
Academic Journal
Introduction: Dynamic advances in therapeutic methods have broadened the range of indications for endoscopic therapy of diseases which have been reserved (so far) for surgical or symptomatic treatment. The quality of life is the best indicator of the efficacy and quality of therapeutic activities undertaken towards a patient. Aim of the study: Assessment of the effect of endoscopic treatment of bile ducts and pancreatic disorders on patients' general quality of life in its various aspects. Material and methods: 55 patients have took a part in the research. They were put into four subgroups: with diagnosed choledocholithiasis, bile ducts neoplasms, organized pancreatic necrosis and chronic pancreatitis. The treatment included endoscopic sphincterotomy, bile ducts and pancreatic stents placement and active transpapillary and transmural drainage. The instruments applied to measure the quality of life included: questionnaires of the European Organization for Research and Treatment of Cancer (EORTC) - QLQ-C30 and QLQ-PAN26, Hospital Anxiety and Depression Scale (HADS-M) and Cantril Ladder. Results: Analysis of the general assessment of the health condition and the quality of life revealed a difference between the results for particular diagnoses. In the group with bile ducts neoplasms, no change of the investigated parameter was observed, while the biggest difference was seen in the patients with choledocholithiasis. Endotherapy considerably lowered the anxiety in the group of the patients with choledocholithiasis and pancreatic necrosis. In all the investigated groups, the patients reported less severe pain. Conclusions: Endoscopic treatment of choledocholithiasis improves patients' general quality of life, while it has no such effect in patients with neoplastic stenosis of the bile ducts. The most visible increase in all the functional scales and in the majority of scales describing symptoms was seen in the patients with choledocholithiasis.


Related Articles

  • Hospitalization, Frequency of Interventions, and Quality of Life after Endoscopic, Surgical, or Conservative Treatment in Patients with Chronic Pancreatitis. Rutter, Karoline; Ferlitsch, A.; Sautner, T.; Püspök, A.; Götzinger, P.; Gangl, A.; Schindl, M. // World Journal of Surgery;Nov2010, Vol. 34 Issue 11, p2642 

    Objective: Patients with chronic pancreatitis usually have a long and debilitating history of disease with frequent hospital admissions, episodes of intractable pain and multiple interventions. The sequences of treatment at initial presentation, endoscopy, surgery, or conservative treatment may...

  • Endoscopic Palliation for Pancreatic Cancer. Bakhru, Mihir; Tekola, Bezawit; Kahaleh, Michel // Cancers;2011, Vol. 3 Issue 2, p1947 

    Pancreatic cancer is devastating due to its poor prognosis. Patients require a multidisciplinary approach to guide available options, mostly palliative because of advanced disease at presentation. Palliation including relief of biliary obstruction, gastric outlet obstruction, and cancer-related...

  • Systematic review of the role of thoracoscopic splanchnicectomy in palliating the pain of patients with chronic pancreatitis. Baghdadi, Saleh; Abbas, M. Hasan; Albouz, Farah; Ammori, Basil J. // Surgical Endoscopy;Mar2008, Vol. 22 Issue 3, p580 

    The management of opiate-dependent intractable abdominal pain caused by chronic pancreatitis remains challenging. The published series on the role, safety, feasibility, and efficacy of thoracoscopic splanchnicectomy are reviewed. The MEDLINE, EMBASE, and PREMEDLINE databases were searched, and...

  • Bilateral Thoracoscopic Splanchnicectomy for Pain Control in Chronic Pancreatitis. Hammond, Bethanie; Vitale, Gary C.; Rangnekar, Nick; Vitale, Emily A.; Binford, John C. // American Surgeon;Jun2004, Vol. 70 Issue 6, p546 

    The purpose of this study was to evaluate prospectively the efficacy of bilateral thoracoscopic splanchnicectomy (TS) for pain due to chronic pancreatitis. Pain is invariably a major debilitating factor in the course of chronic pancreatitis. This study was performed to evaluate the effect of...

  • Long-term health-related quality of life after minimally invasive surgery for diverticular disease. Scarpa, Marco; Griggio, Luciano; Rampado, Sabrina; Ruffolo, Cesare; Citton, Marilisa; Pozza, Anna; Borsetto, Lara; Dall'Olmo, Luigi; Angriman, Imerio // Langenbeck's Archives of Surgery;Aug2011, Vol. 396 Issue 6, p833 

    Background and aims: The aim of this multicentric study was to evaluate the disease specific and the generic quality of life in patients affected by colonic diverticular disease (DD) who had undergone minimally invasive or open colonic resection or who had been treated with medical therapy in...

  • Minimal Access Surgery (Laparoscopic Cardiomyotomy) for Achalasia Cardia. Patil, Hemant // World Journal of Laparoscopic Surgery;Jan-Apr2009, Vol. 2 Issue 1, p1 

    Background: Primary motor disorder of esophagus is achalasia cardia which is progressive in nature and do not have any definitive cure. Esophageal cardiomyotomy is the palliative method of treatment Which forms the backbone of the treatment line of management. Over a period of last few years...

  • An Improvement in the Quality of Life after Performing Endoscopic Balloon Dilation for Postoperative Anastomotic Stricture of the Rectum. Kan, Hayato; Furukawa, Kiyonori; Suzuki, Hideyuki; Tsuruta, Hiroyuki; Matsumoto, Satoshi; Akiya, Yukihiro; Teranishi, Nobuhisa; Sasaki, Junpei; Tajiri, Takashi // Journal of Nippon Medical School;2007, Vol. 74 Issue 6, p418 

    A 55-year-old woman underwent a low anterior resection for rectal cancer 7 years earlier at a different hospital. Thereafter, she often had such symptoms as abdominal pain, frequent bowel movements, and constipation. We considered postoperative bowel adhesion to be the cause of these symptoms,...

  • Pain and pain generation in pancreatic cancer. di Mola, Fabio F.; di Sebastiano, Pierluigi // Langenbeck's Archives of Surgery;Nov2008, Vol. 393 Issue 6, p919 

    Pain can be a frequent symptom during the natural history of a patient with pancreatic cancer. An increase in incidence with disease progression and the presence of unbearable pain may preclude a curative resection. Even in those patients with resectable pancreatic cancer, the presence of pain...

  • Myofibroblastic Inflammatory Tumor Presenting as Recurrent Acute Pancreatitis and Obstructive Jaundice. Carmen-Monica Preda; Mihnea Ionescu; Traian Dumitrascu; Mircea Manuc; Corina Meianu; Vlad Herlea // Journal of Gastrointestinal & Liver Diseases;Sep2015, Vol. 24 Issue 3, p273 

    The article discusses the myofibroblastic inflammatory tumor presenting as recurrent acute pancreatitis and obstructive jaundice in a 38 year-old male patient, who was a smoker, with occasional alcohol consumption, episodes of high blood pressure and recurrent acute pancreatitis. Clinical...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics