TITLE

Plasma levels of peptide YY in differently fed infants

AUTHOR(S)
Tomasik, Przemyslaw J.; Fyderek, Krzysztof; Sztefko, Krystyna
PUB. DATE
May 2009
SOURCE
Gastroenterologia Polska / Gastroenterology;2009, Vol. 16 Issue 3, p207
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Introduction: Gastrointestinal peptide YY (PYY) is a well-known satiety signal. Its role as an anti-inflammatory agent was recently disclosed. The aim of study was to measure the PYY plasma concentrations in infants fed with different formulas. Material and methods: The infants were divided into three age-matched groups: group I (13 healthy breast-fed children), group II (13 healthy infants on a cow's milk formula), and group III (12 infants on cow's milk with a hydrolyzed protein formula). Blood samples were collected before and 60 minutes after the meal. The plasma levels of PYY were determined by EIA. Results: The lowest mean PYY concentrations were found in the breast-fed children, both fasting (0.92±0.3 ng/ml) and after the meal (1.22±0.28 ng/ml). Significantly higher concentrations of PYY than in groups I and III were observed in the milk formula-fed children (before meal: 1.74±0.39 ng/ml, after: 2.1±0.34 ng/ml, p<0.001 in both cases). In group III the fasting values did not differ from those obtained after the meal (1.18±0.33 ng/ml and 1.14±0.25 ng/ml, respectively). Conclusion: The differences in PYY level among the groups fed the same caloric load suggest that this peptide play a role other than that of a satiety factor in infants.
ACCESSION #
44833890

 

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