Cardiac Cell Repair Therapy: A Clinical Perspective
- Stem Cell Therapy and Regenerative Medicine. O'Brien, Timothy; Barry, P. // Mayo Clinic Proceedings;Oct2009, Vol. 84 Issue 10, p859
The author reflects on the significance of stem cell therapy to address the clinical needs for cardiac repair and bone disorders. He relates to the two clinical studies conducted to patients with myocardial infraction (MI) in which the study of B. J. Gersch and colleagues has shown improvements...
- Early Lineage Adult Regenerative Cells Offer Promising New Cell-based Therapy. Ritter, Amy // BioPharm International;Apr2011, Vol. 24 Issue 4, p10
The article offers information on the cell-based therapy provided by early lineage adult (ELLA) regenerative cells, developed by Parcell Laboratories of Massachusetts.
- Cell Sheet-Based Myocardial Tissue Engineering: New Hope for Damaged Heart Rescue. Shimizu, Tatsuya; Sekine, Hidekazu; Yamato, Masayuki; Okano, Teruo // Current Pharmaceutical Design;8/21/2009, Vol. 15 Issue 24, p2807
Regenerative therapy has currently emerged as one of the most promising treatments for the patients suffering from severe heart failure. Several cell therapies by direct injection have been already clinically performed. However, significant cell loss due to physical strain, primary hypoxia or...
- Innovation in Basic Science: Stem Cells and their role in the treatment of Paediatric Cardiac Failure - Opportunities and Challenges. Kaushal, Sunjay; Jacobs, Jeffrey Phillip; Gossett, Jeffrey G.; Steele, Ann; Steele, Peter; Davis, Craig R.; Pahl, Elfriede; Vijayan, Kalpana; Asante-Korang, Alfred; Boucek, Robert J.; Backer, Carl L.; Wold, Loren E. // Cardiology in the Young;Nov2009 Supplement, Vol. 19 Issue S2, p74
Heart failure is a leading cause of death worldwide. Current therapies only delay progression of the cardiac disease or replace the diseased heart with cardiac transplantation. Stem cells represent a recently discovered novel approach to the treatment of cardiac failure that may facilitate the...
- Coalition aims to accelerate translation of cell therapies. Sinha, Gunjan // Nature Biotechnology;Jul2012, Vol. 30 Issue 7, p573
The article reports that spokespersons of six translational medicine centers working on cell based therapies met in Berlin, Germany to initiate the Regenerative Medicine Coalition (RMC). Frank-Roman Lauter, head of business development at Berlin-Brandenburg Center for RegenerativeTherapies in...
- Novel Strategies of Regenerative Medicine Using Chemical Compounds. Lasagni, L.; Sagrinati, C.; Ronconi, E.; Angelotti, M. L.; Parente, E.; Ballerini, L.; Peired, A.; Romagnani, P. // Current Medicinal Chemistry;Dec2010, Vol. 17 Issue 34, p4134
No abstract available.
- Applications of Amniotic Membrane and Fluid in Stem Cell Biology and Regenerative Medicine. Rennie, Kerry; Gruslin, Andrée; Hengstschläger, Markus; Duanqing Pei; Jinglei Cai; Toshio Nikaido; Mahmud Bani-Yaghoub // Stem Cells International;2012, p1
The amniotic membrane (AM) and amniotic fluid (AF) have a long history of use in surgical and prenatal diagnostic applications, respectively. In addition, the discovery of cell populations in AM and AF which are widely accessible, nontumorigenic and capable of differentiating into a variety of...
- Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions. Cao, Nan; Liang, He; Huang, Jijun; Wang, Jia; Chen, Yixiong; Chen, Zhongyan; Yang, Huang-Tian // Cell Research;Sep2013, Vol. 23 Issue 9, p1119
Cardiovascular progenitor cells (CVPCs) derived from human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), hold great promise for the study of cardiovascular development and cell-based therapy of heart diseases, but...
- Focus on regenerative medicine. // Nature Biotechnology;Aug2014, Vol. 32 Issue 8, pvii
An introduction is presented in which the author discusses articles within the issue on topics including regenerative medicine, age-related macular degeneration, and cell therapy.