CTX-M enzymes are the predominant extended-spectrum β-lactamases produced by Enterobacteriaceae in Ireland

Morris, Dearbháile; Boyle, Fiona; Buckley, Victoria; Li Xu; Hanahoe, Belinda; Hawkey, Peter; Cormican, Martin
October 2009
Journal of Antimicrobial Chemotherapy (JAC);Oct2009, Vol. 64 Issue 4, p864
Academic Journal
The article presents a study that deals with the predominance of CTX-M ß-lactamases among extended-spectrum ß-lactamase-producing Enterobacteriaceae in Ireland. Focal to the study was a nationwide survey of ESBL-PE collected throughout Ireland over an 11 year period. It highlighted the predominance of CTX-M producing strains. Included in the study were 812 isolates of Enterobacteriaceae received from 25 clinical laboratories from 1997 to 2007. Based on their investigation, the authors attributed the widespread dissemination of Enterobacteriaceae producing CTX-M-15 and CTX-M-14 to foreign travel and was spread by levels of antimicrobial consumption.


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