TITLE

Gastroesophageal Reflux Symptoms in a Danish Population: A Prospective Follow-Up Analysis of Symptoms, Quality of Life, and Health-Care Use

AUTHOR(S)
Hansen, Jane Møller; Wildner-Christensen, Mette; Schaffalitzky de Muckadell, Ove B
PUB. DATE
October 2009
SOURCE
American Journal of Gastroenterology;Oct2009, Vol. 104 Issue 10, p2394
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
OBJECTIVES:The prevalence of gastroesophageal reflux symptoms (GERS) in the population is high; however, data on long-term follow-up and incidence of GERS in the population are sparse. This study describes the long-term natural history of GERS, the related health-care use, and quality of life in a population followed up for 5 years.METHODS:A total of 10,000 randomly selected inhabitants, 40–65 years old, received, as a part of a controlled trial of Helicobacter pylori screening and treatment (control group), a mailed questionnaire regarding demographic data, gastrointestinal symptoms (the Gastrointestinal Symptom Rating Scale (GSRS)), and quality of life (the Short-Form 36-Item Health Survey (SF-36)) at inclusion and after 5 years. GERS was defined as a mean score ≥2 in the reflux dimension in the GSRS. Information on use of health-care resources was drawn from the questionnaires and registers.RESULTS:In all, 6,781 individuals answered the first questionnaire and 5-year symptom data were complete for 5,578 (82.3%) of them. The mean age at inclusion was 52.4 years, 48% were men. At inclusion, 22% reported GERS. During follow-up, symptoms resolved in 43%, of whom 10% received acid inhibitory treatment at 5-year follow-up. The incidence of GERS was 2.2% per year. Health-care use during follow-up was significantly higher in individuals with GERS at baseline than in individuals without GERS. Quality of life at 5-year follow-up was lower in individuals with GERS at inclusion than in individuals without GERS at inclusion.CONCLUSIONS:GERS are prevalent, long lasting, and associated with an impaired quality of life and substantial health-care use.
ACCESSION #
44461534

 

Related Articles

  • Changes in prevalence, incidence and spontaneous loss of gastro-oesophageal reflux symptoms: a prospective population-based cohort study, the HUNT study. Ness-Jensen, Eivind; Lindam, Anna; Lagergren, Jesper; Hveem, Kristian // Gut;Oct2012, Vol. 61 Issue 10, p1390 

    Objective Changes in the occurrence of gastrooesophageal reflux symptoms (GORS) in the population remain uncertain. This study aimed to determine the prevalence changes, the incidence and the spontaneous loss of GORS. Design This population-based cohort study was conducted within the...

  • Prevalence of Uninvestigated Dyspepsia and Gastroesophageal Reflux Disease in Korea: A Population-Based Study Using the Rome III Criteria. Min, Byung-Hoon; Huh, Kyu; Jung, Hye-Kyung; Yoon, Young; Choi, Kee; Song, Kyung; Keum, Bora; Kim, Jung // Digestive Diseases & Sciences;Nov2014, Vol. 59 Issue 11, p2721 

    Background/Aims: There have been few population-based studies on the prevalences of gastroesophageal reflux disease (GERD) and dyspepsia using Rome III criteria in Asian countries. Methods: A population-based, cross-sectional study was conducted by telephone interviews of 5,000 Koreans between...

  • A comparison of two approaches for assessing patient importance weights to conduct an Extended Q-TWiST analysis. Schwartz, Carolyn E.; Mathias, Susan D.; Pasta, David J.; Colwell, Hilary H.; Rapkin, Bruce D.; Genderson, M. Wilson; Henning, James M.; Schwartz, C E; Mathias, S D; Pasta, D J; Colwell, H H; Rapkin, B D; Genderson, M W; Henning, J M // Quality of Life Research;May1999, Vol. 8 Issue 3, p197 

    Objective: Patient-centered methods for evaluating treatments require validated preference-elicitation techniques. We describe the validation of two preference-elicitation approaches for use in an Extended Q-TWiST treatment evaluation. The first method was an "idiographic" approach,...

  • Atypical Symptoms in Patients With Gastroesophageal Reflux Disease. Yi, Chih-Hsun; Liu, Tso-Tsai; Chen, Chien-Lin // Journal of Neurogastroenterology & Motility;Jul2012, Vol. 18 Issue 3, p278 

    Background/Aims: Atypical symptoms are common in gastroesophageal reflux disease (GERD). Patients with non-erosive reflux disease (NERD) and erosive reflux disease (ERD) exhibit different clinical characteristics and responses to acid suppression treatment. We aimed to compare atypical...

  • Survey on the prevalence of GERD and FD based on the Montreal definition and the Rome III criteria among patients presenting with epigastric symptoms in Japan. Ohara, Shuichi; Kawano, Tatsuyuki; Kusano, Motoyasu; Kouzu, Teruo // Journal of Gastroenterology;May2011, Vol. 46 Issue 5, p603 

    Background: The present survey aimed to clarify the prevalence of gastroesophageal reflux disease (GERD) and functional dyspepsia (FD) in patients presenting with epigastric symptoms in Japan based on the Montreal definition and the Rome III criteria, respectively, and to determine the degree of...

  • Endoscopic full-thickness plication versus laparoscopic fundoplication: a prospective study on quality of life and symptom control. Antoniou, Stavros; Koch, Oliver; Kaindlstorfer, Adolf; Asche, Kai; Berger, Johannes; Granderath, Frank; Pointner, Rudolph // Surgical Endoscopy;Apr2012, Vol. 26 Issue 4, p1063 

    Background: Endoscopic antireflux techniques have emerged as alternative therapies for gastroesophageal reflux disease (GERD). Endoscopic plication receives continuing interest as an effective and safe procedure. This treatment option has not been the subject of comparison with well-established...

  • Is Easier the Better in a Feasibility Study of Questionnaires? Jung Ho Park // Journal of Neurogastroenterology & Motility;Jan2013, Vol. 19 Issue 1, p3 

    The article focuses on the simplified questionnaires developed to assess the frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) and quality of life and utility evaluation survey technology (QUEST) for diagnosing gastroesophageal reflux disease (GERD). It mentions that the...

  • Nonerosive Reflux Disease -- Current Concepts and Dilemmas. Fass, Ronnie; Fennerty, Brian; Vakil, Nimish // American Journal of Gastroenterology;Feb2001, Vol. 96 Issue 2, p303 

    Nonerosive reflux disease is defined as the presence of typical symptoms of gastroesophageal reflux disease caused by intraesophageal acid in the absence of visible esophageal mucosal injury at endoscopy. Recent studies demonstrate that it is a chronic disease with a significant impact on...

  • Gastroesophageal Reflux Symptoms and Well-Being in a Random Sample of the General Population of a Swedish Community. Wiklund, Ingela; Carlsson, Jonas; Vakil, Nimish // American Journal of Gastroenterology;Jan2006, Vol. 101 Issue 1, p18 

    OBJECTIVES: There is limited information on the relationship between gastroesophageal reflux symptoms and well-being in the general population. This study aimed to investigate this relationship and determine the severity threshold at which reflux symptoms meaningfully affect patients'...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics