TITLE

Direct immobilization of enzymes in GaN and InN nanocolumns: The urease case study

AUTHOR(S)
Sofikiti, N.; Chaniotakis, N.; Grandal, J.; Utrera, M.; Sanchez-Garcia, M. A.; Calleja, E.; Iliopoulos, E.; Georgakilas, A.
PUB. DATE
September 2009
SOURCE
Applied Physics Letters;9/14/2009, Vol. 95 Issue 11, p113701
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In this work, the development of potentiometric urea biosensors through the entrapment of urease enzyme within the cavities of nanocolumnar GaN and InN wurtzite semiconductor substrates, is being described. The biosensing capabilities of these materials are compared with biosensors based on the corresponding flat surfaces, in order to check the increased sensitivity and enzyme stabilization properties expected from the nanocolumns. The obtained results proved that the electrochemically active nanocolumns serve both as highly sensitive transducer, as well as stabilizing nanoenvironment within which urease retains its catalytic activity for a prolonged period of time.
ACCESSION #
44292282

 

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