Virological, Clinical, and Ophthalmologic Features of Cytomegalovirus Retinitis after Hematopoietic Stem Cell Transplantation
Tags: CYTOMEGALOVIRUS infections; HEMATOPOIETIC stem cells -- Transplantation
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This trial was designed to compare foscarnet with ganciclovir as pre-emptive therapy for CMV infection in patients undergoing allogeneic hemopoietic stem cell transplant (HSCT). Thirty-nine patients were randomized to receive foscarnet 90 mg/kg every 12 h (n = 20) or ganciclovir 5 mg/kg every 12...
- Prevention and management of CMV-related problems after hematopoietic stem cell transplantation. Zaia, J.A. // Bone Marrow Transplantation;4/15/2002, Vol. 29 Issue 8, p633
Addresses certain practical problems that commonly arise in the prevention and management of human cytomegalovirus (CMV) infection after hematopoietic stem cell transplantation. Description of the persons who are at risk for CMV disease; Insight on the best diagnostic options; Recommendations.
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In total, 11 consecutive pediatric patients with Griscelli syndrome (GS) type 2, who received allogeneic hematopoietic SCT (aHSCT) at our center between 1993 and 2007, were reviewed. The median age at transplantation was 8.2 months (range, 4�36.3 months) and the median time from diagnosis to...
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Low public awareness of cytomegalovirus (CMV) results from the only mild and transient symptoms that it causes in the healthy immunocompetent host, so that primary infection usually goes unnoticed. The virus is not cleared, however, but stays for the lifetime of the host in a non-infectious,...
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Reactivation of latent cytomegalovirus (CMV) in the transient state of immunodeficiency after hematopoietic cell transplantation (HCT) is the most frequent and severe viral complication endangering leukemia therapy success. By infecting the bone marrow (BM) stroma of the transplantation...
- Signature profiles of CMV-specific T-cells in patients with CMV reactivation after hematopoietic SCT. Król, L.; Stuchlý, J.; Hubáček, P.; Keslová, P.; Sedláček, P.; Starý, J.; Hrušák, O.; Kalina, T. // Bone Marrow Transplantation;Aug2011, Vol. 46 Issue 8, p1089
Depletion of cellular immunity as a consequence of conditioning before allogeneic hematopoietic SCT (HSCT) frequently results in CMV reactivation, which may in turn lead to life-threatening infections and require timely antiviral treatment. We have investigated the functional signatures of...
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Purpose: This study was performed in order to evaluate the incidence and characteristics of cytomegalovirus (CMV) infection in children with acute leukemia according to donor source and graft type. Materials and Methods: We retrospectively identified children with acute leukemia who had received...
- Suspected delayed immune recovery against cytomegalovirus after reduced-intensity stem cell transplantation using anti-thymocyte globulin. Nakai, K.; Kanda, Y.; Mineishi, S.; Saito, T.; Ohnishi, M.; Niiya, H.; Chizuka, A.; Takeuchi, T.; Matsubara, H.; Kami, M.; Makimoto, A.; Tanosaki, R.; Kunitoh, H.; Tobinai, K.; Takaue, Y. // Bone Marrow Transplantation;2/1/2002, Vol. 29 Issue 3, p237
Presents a study which examined the clinical characteristics of cytomegalovirus to determine if the incidence of opportunistic infection increase after reduced-intensity hematopoietic stem cell transplantation (RIST). Background on RIST; Data and methods used; Findings.
- Epidemiology of cytomegalovirus disease in solid organ and hematopoietic stem cell transplant recipients. Razonable, Raymund R. // American Journal of Health-System Pharmacy;4/15/2005 Supplement 1, Vol. 62, pS7
Purpose. The novel and traditional risk factors for cytomegalovirus (CMV) infection and disease in solid organ transplant (SOT) and hematopoietic stem cell transplant (HSCT) recipients, the current strategies for the prevention of CMV disease, the emerging syndrome of late-onset CMV disease, and...
