Protective Gene, Longer Life

October 2009
PN;Oct2009, Vol. 63 Issue 10, p55
Trade Publication
The article reports on a new genetic discovery that offers a deeper understanding of amyotrophic lateral sclerosis (ALS) disease processe and that could improve survival in people with ALS. It mentions that it supports the theory that the death of motor neurons is caused by the changes in cellular transport. It details how the study was conducted. John Landers of the University of Massachusetts Medical School, notes the significance of the discovery since it provides clue on ALS progression.


Related Articles

  • Minocycline in amyotrophic lateral sclerosis: a pilot study. Pontieri, F. E.; Ricci, A.; Pellicano, C.; Benincasa, D.; Buttarelli, F. R. // Neurological Sciences;Oct2005, Vol. 26 Issue 4, p285 

    Recent studies indicate that minocycline exerts neuroprotective effects in vitro and in vivo, and suggest that the drug may represent a novel therapeutic approach to amyotrophic lateral sclerosis (ALS). In this study we investigated the safety of combined treatment with minocycline and riluzole...

  • All that ripples is not "Motor neuron disease.". Panagariya, Ashok; Agarwal, Vinay; Agarwal, Neeraj // Annals of Indian Academy of Neurology;Apr2007, Vol. 10 Issue 2, p88 

    Until early 80's most patients presenting with lower motor neuron syndrome characterized by weakness, wasting, diminished reflexes, fasciculations, cramps and minimal sensory involvement would have been diagnosed as motor neuron disease- LMN variant. But similar clinical picture can be seen in...

  • Promising riboflavin treatment for motor neuron disorder. Timmerman, Vincent; De Jonghe, Peter // Brain: A Journal of Neurology;Jan2014, Vol. 137 Issue 1, p2 

    No abstract available.

  • Weaning from prolonged invasive ventilation in motor neuron disease: analysis of outcomes and survival. R Chadwick // Journal of Neurology, Neurosurgery & Psychiatry;Jun2011, Vol. 82 Issue 6, p643 

    INTRODUCTION: Non-invasive ventilation (NIV) improves prognosis in patients with motor neuron disease (MND) in the absence of major bulbar involvement. However, some experience a rapid and unexpected decline in respiratory function and may undergo emergency tracheal intubation. Weaning from...

  • Opioid medication in the palliative care of motor neurone disease. Oliver, D. // Palliative Medicine;1998, Vol. 12 Issue 2, p113 

    In the palliative care of patients with motor neurone disease (MND) symptoms are encountered that can be helped by the use of strong opioid medication. A retrospective survey of the 32 patients dying of MND at the Wisdom Hospice who required opioids showed that 75% received oral opioids, 94%...

  • Assisting people diagnosed with motor neurone disease. Swann, Julie // British Journal of Healthcare Assistants;Apr2011, Vol. 5 Issue 4, p174 

    Motor neurone disease is a group of progressive neuromuscular diseases in which nerve cells die and leave voluntary muscles paralysed. It can affect men and women and occurs in people of all ethnicities. This article explains motor neurone disease, its impact on newly diagnosed patients and how...

  • Motor neurone disease: research, treatment and care. Swann, Julie // British Journal of Healthcare Assistants;May2011, Vol. 5 Issue 5, p229 

    Clinicians and researchers do not fully understand why motor neurone disease (MND) occurs, but they know how the body is affected. Unfortunately, this means that there is currently no cure for MND and the disease cannot be prevented, although the symptoms of the various forms of MND can be...

  • Targeting the full length of the motor end plate regions in the mouse forelimb increases the uptake of Fluoro-Gold into corresponding spinal cord motor neurons. Tosolini, Andrew Paul; Mohan, Rahul; Morris, Renée // Frontiers in Neurology;May2013, Vol. 4, p1 

    Lower motor neuron dysfunction is one of the most debilitating motor conditions. In this regard, transgenic mouse models of various lower motor neuron dysfunctions provide insight into the mechanisms underlying these pathologies and can also aid the development of new therapies. Viral-mediated...

  • New culprit found in Lou Gehrig's disease; second 'bad' gene is linked to damaged cell buildup, paralysis in ALS.  // Biomedical Market Newsletter;11/21/2011, Vol. 21, p56 

    The article discusses the findings of the study about the impact of the genes, sequestosomel and ubiquilin2 in patients with amyotrophic lateral sclerosis (ALS and Lou Gehrig's disease) in Chicago, Illinois. According to the study, patients become paralyzed because they accumulate abnormally in...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics