TITLE

Simultaneous determination of optical and acoustic thicknesses of protein layers using surface plasmon resonance spectroscopy and quartz crystal microweighing

AUTHOR(S)
Laschitsch, Alexander; Menges, Bernhard; Johannsmann, Diethelm
PUB. DATE
October 2000
SOURCE
Applied Physics Letters;10/2/2000, Vol. 77 Issue 14
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The optical and the acoustic thicknesses of protein layers during adsorption were simultaneously determined by a combination of surface plasmon resonance spectroscopy and quartz crystal microweighing. Coupling of the surface plasmon was achieved by etching a diffraction grating into the quartz surface prior to the deposition of the metal electrode. The evolution of the acoustic and the optical thickness was markedly different, which is attributed to surface roughness and partial coverage. © 2000 American Institute of Physics.
ACCESSION #
4412831

 

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