TITLE

Formulation and evaluation of fast dispersible tablets of aceclofenac

AUTHOR(S)
Shivprasad, Majumdar; Dhiraj, Nikam
PUB. DATE
August 2009
SOURCE
Journal of Pharmacy Research;Aug2009, Vol. 2 Issue 8, p1296
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Aceclofenac a non-steroidal anti-inflammatory drug, used in posttraumatic pain and rheumatoid arthritis. Aceclofenac fast-dispersible tablet have been prepared by direct compression method using microcrystalline cellulose as a direct compressible vehicle. Croscarmellose sodium and polyplasdone xl-10 were used as a superdisintegrants for the formulation. The disintegration time and dissolution parameter (t50% and t80%) decreased with increasing the concentration of polyplasdone. Those tablets were evaluated for weight variation, hardness, disintegration time, friability and dissolution.
ACCESSION #
43935488

 

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