TITLE

Bulky extramedullary hematopoiesis is not a rare complication of congenital dyserythropoietic anemia

AUTHOR(S)
Heimpel, Hermann; Dührsen, Ulrich; Hofbauer, P.; Rigamonti-Wermlinger, V.; Kreuser, Ernst-Dietrich; Schwarz, Klaus; Solenthaler, Max; Pauls, S.
PUB. DATE
October 2009
SOURCE
Annals of Hematology;Oct2009, Vol. 88 Issue 10, p937
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Bulky extramedullary hematopoiesis, usually detected in the thorax by imaging techniques, is a well-known complication in many types of congenital anemias. Here, we describe 12 cases of congenital dyserythropoietic anemia with extramedullary hematopoiesis which was always located in the paravertebral space of the thoracic spine and in other paraspinal regions in a few cases. All bulks were originally detected in chest radiographs and confirmed by imaging techniques such as computed tomography and/or magnetic resonance imaging. In some cases, thoracotomy was performed for suspected malignancy. Although the true prevalence is not known, paravertebral masses in patients with CDA of any type are not uncommon and should be the first differential diagnosis considered when masses adjacent to the spine are detected in this disorder.
ACCESSION #
43757821

 

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