Direct observation of the tip shape in scanning probe microscopy

Montelius, L.; Tegenfeldt, J.O.
May 1993
Applied Physics Letters;5/24/1993, Vol. 62 Issue 21, p2628
Academic Journal
Examines the shape of the atomic force microscopy (AFM) tip. Dependence of microscopy forces on the actual tip size; Comparison of the AFM image cantilever shape with the actual shape; Interaction between the tip material and biomolecules; Possibility of reverse imaging of objects positioned on the AFM tip.


Related Articles

  • High-speed AFM and nano-visualization of biomolecular processes. Ando, Toshio; Uchihashi, Takayuki; Kodera, Noriyuki; Yamamoto, Daisuke; Miyagi, Atsushi; Taniguchi, Masaaki; Yamashita, Hayato // Pflugers Archiv European Journal of Physiology;Apr2008, Vol. 456 Issue 1, p211 

    Conventional atomic force microscopes (AFMs) take at least 30–60 s to capture an image, while dynamic biomolecular processes occur on a millisecond timescale or less. To narrow this large difference in timescale, various studies have been carried out in the past decade. These efforts have...

  • Attractive-mode force microscope for investigations of biomolecules under ambient conditions. King, G. M.; Nunes, G. // Review of Scientific Instruments;Nov2001, Vol. 72 Issue 11, p4261 

    We report on the design and performance of a quartz tuning-fork-based dynamic mode atomic force microscope for the imaging of biological samples under ambient conditions. The instrument uses a stiff cantilever that maintains stable oscillations at low amplitudes even in the presence of capillary...

  • Improved atomic force microscope images using microcantilevers with sharp tips. Akamine, S.; Barrett, R. C.; Quate, C. F. // Applied Physics Letters;7/16/1990, Vol. 57 Issue 3, p316 

    Novel force-sensing microcantilevers with sharp tips have been used to obtain atomic force microscope images of atomically flat, layered compounds as well as microfabricated samples with large-scale topographies. When imaging atomically flat samples using cantilevers with sharp protruding tips,...

  • Atomic resolution imaging of a nonconductor by atomic force microscopy. Albrecht, T. R.; Quate, C. F. // Journal of Applied Physics;10/1/1987, Vol. 62 Issue 7, p2599 

    Presents a study that examined the capability of the atomic force microscope in imaging the surface of an electrically insulating solid with atomic resolution. Background on atomic force microscopy; Analysis of the lever-sample interaction; Results and implications.

  • High-speed atomic force microscopy in liquid. Sulchek, T.; Hsieh, R.; Adams, J. D.; Adams, J.D.; Minne, S. C.; Minne, S.C.; Quate, C. F.; Quate, C.F.; Adderton, D. M.; Adderton, D.M. // Review of Scientific Instruments;May2000, Vol. 71 Issue 5 

    High-speed constant force imaging with the atomic force microscope (AFM) has been achieved in liquid. By using a standard optical lever AFM, and a cantilever with an integrated zinc oxide (ZnO) piezoelectric actuator, an imaging bandwidth of 38 kHz has been achieved; nearly 100 times faster than...

  • Tapping-mode atomic force microscopy and phase-imaging in higher eigenmodes. Stark, Robert W.; Drobek, Tanja // Applied Physics Letters;5/31/1999, Vol. 74 Issue 22, p3296 

    Explores the use of tapping-mode atomic force microscopy to study soft biological samples. Sensitivity of the tapping probe; Effects of higher eigenmodes of the vibrating cantilever; Suitability for imaging applications.

  • High-speed tapping mode imaging with active Q control for atomic force microscopy. Sulchek, T.; T. Sulchek; Hsieh, R.; Adams, J. D.; Adams, J.D.; Yaralioglu, G. G.; Yaralioglu, G.G.; Minne, S. C.; Minne, S.C.; Quate, C. F.; Quate, C.F.; Cleveland, J. P.; Cleveland, J.P.; Atalar, A.; Adderton, D. M.; Adderton, D.M. // Applied Physics Letters;3/13/2000, Vol. 76 Issue 11 

    The speed of tapping mode imaging with the atomic force microscope (AFM) has been increased by over an order of magnitude. The enhanced operation is achieved by (1) increasing the instrument's mechanical bandwidth and (2) actively controlling the cantilever's dynamics. The instrument's...

  • Comparative Study of Atomic Force Imaging of DNA on Graphite and Mica Surfaces. Klinov, Dmitry; Dwir, Benjamin; Kapon, Eli; Borovok, Natalia; Molotsky, Tatiana; Kotlyar, Alexander // AIP Conference Proceedings;2006, Vol. 859 Issue 1, p99 

    Various DNA-based structures (single-, double-, triple-stranded and quadruplex-DNA) were characterized using non-contact atomic-force microscopy on two substrates: modified highly-oriented pyrolitic graphite (HOPG) and mica. Deposition on mica, a conventional substrate used in studies of...

  • Biophysics (communication arising): Is rhodopsin dimeric in native retinal rods? Fotiadis, Dimitrios; Liang, Yan; Filipek, Slawomir; Saperstein, David A.; Engel, Andreas; Palczewski, Kryzsztol // Nature;11/6/2003, Vol. 426 Issue 6962, p31 

    Individual biological molecules can be imaged under physiological conditions by atomic force microscopy. Our results from AFM, supported by electron microscopy, revealed distinct rows of rhodopsin dimers and paracrystalline arrays in native murine disc membranes. This supramolecular arrangement...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics