TITLE

On the origin of the histone fold

PUB. DATE
January 2007
SOURCE
BMC Structural Biology;2007, Vol. 7, p17
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
43718218

 

Related Articles

  • -In silico functional characterization of a double histone fold domain from the Heliothis zea virus I. Greco, Claudio; Fantucci, Piercarlo; Gioia, Luca De // BMC Bioinformatics;2005 Supplement 4, Vol. 6, p1 

    Background: Histones are short proteins involved in chromatin packaging; in eukaryotes, two H2a-H2b and H3-H4 histone dimers form the nucleosomal core, which acts as the fundamental DNA-packaging element. The double histone fold is a rare globular protein fold in which two consecutive regions...

  • histone.  // Taber's Cyclopedic Medical Dictionary;2005, p1002 

    A definition of the medical term "histone" is presented. Histone refers to one of the five kinds of proteins that are part of chromatin in eukaryotic cells. Their positive charge attracts the negatively charged DNA that is folded around them into units called nucleosomes. Histones also regulate...

  • Crystal structure of the nucleosome core particle at 2.8 A resolution. Luger, Karolin; Mader, Armin W. // Nature;9/18/1997, Vol. 389 Issue 6648, p251 

    Presents research which asserts that the X-ray crystal structure of the nucleosome core particle of chromatin shows in atomic detail how the histone protein octamer is assembled and the organization of DNA base pairs. Histone/histone and histone/DNA interactions; Histone amino-terminal tails;...

  • The Hydrophobicity of the H3 Histone Fold differs from the Hydrophobicity of the other three Folds. Silverman, B. // Journal of Molecular Evolution;Mar2005, Vol. 60 Issue 3, p354 

    The eukaryotic histone dimers, H3-H4 and H2A-H2B, are formed in the cytosol prior to being transported into the nucleus and assembled into the nucleosome. Residue side-chain distances from the interior of the histone dimers are obtained with an ellipsoidal spatial metric and structural...

  • The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution. Bowman, Andrew; Hammond, Colin M.; Stirling, Andrew; Ward, Richard; Shang, Weifeng; El-Mkami, Hassane; Robinson, David A.; Svergun, Dmitri I.; Norman, David G.; Owen-Hughes, Tom // Nucleic Acids Research;May2014, Vol. 42 Issue 9, p6038 

    NAP-1 fold histone chaperones play an important role in escorting histones to and from sites of nucleosome assembly and disassembly. The two NAP-1 fold histone chaperones in budding yeast, Vps75 and Nap1, have previously been crystalized in a characteristic homodimeric conformation. In this...

  • The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution. Bowman, Andrew; Hammond, Colin M.; Stirling, Andrew; Ward, Richard; Weifeng Shang; El-Mkami, Hassane; Robinson, David A.; Svergun, Dmitri I.; Norman, David G.; Owen-Hughes, Tom // Nucleic Acids Research;May2015, Vol. 43 Issue 9, p6038 

    NAP-1 fold histone chaperones play an important role in escorting histones to and from sites of nucleosome assembly and disassembly. The two NAP-1 fold histone chaperones in budding yeast, Vps75 and Nap1, have previously been crystalized in a characteristic homodimeric conformation. In this...

  • Synthesis of 2-quinolinecarboxamide derivatives as potential HDAC inhibitors. Habarova, O.; Bobiļeva, O.; Loža, E.; Romančikova, N. // Chemistry of Heterocyclic Compounds;Sep2011, Vol. 47 Issue 6, p719 

    Inhibition of histone deacetylase activity appears as an original and effective approach for the treatment of cancer. A series of novel quinoline-containing derivatives has been synthesized and found that some of these compounds possess nanomolar histone deacetylase inhibitory activity.

  • Molecular mechanisms and potential functions of histone demethylases. Kooistra, Susanne Marije; Helin, Kristian // Nature Reviews Molecular Cell Biology;May2012, Vol. 13 Issue 5, p297 

    Histone modifications are thought to regulate chromatin structure, transcription and other nuclear processes. Histone methylation was originally believed to be an irreversible modification that could only be removed by histone eviction or by dilution during DNA replication. However, the...

  • The H2A/H2B-like histone-fold domain proteins at the crossroad between chromatin and different DNA metabolisms. Gnesutta, Nerina; Nardini, Marco; Mantovani, Roberto // Transcription (2154-1264);2013, Vol. 4 Issue 3, p114 

    Core histones are the building block of chromatin and among the most highly conserved proteins in eukaryotes. The related "deviant" histones share the histone-fold domain, and serve various roles in DNA metabolism. We provide here a structural and functional outlook of H2A/H2B-like deviant...

  • The Scottish fold. Helgren, J. Anne // Cats Magazine;Aug96, Vol. 52 Issue 8, p60 

    Presents information about Scottish fold breed of cats. Origin of the Scottish fold breed; Introduction of the breed in the United States; Genetic problems breeding Scottish folds; Susceptibility of folds to ear infection; Scottish fold cats temperament.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics