X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1)

January 2005
BMC Structural Biology;2005, Vol. 5, p21
Academic Journal
No abstract available.


Related Articles

  • Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer. Raymond, Amy; Lovell, Scott; Lorimer, Don; Walchli, John; Mixon, Mark; Wallace, Ellen; Thompkins, Kaitlin; Archer, Kimberly; Burgin, Alex; Stewart, Lance // BMC Biotechnology;2009, Vol. 9, Special section p1 

    Background: With the goal of improving yield and success rates of heterologous protein production for structural studies we have developed the database and algorithm software package Gene Composer. This freely available electronic tool facilitates the information-rich design of protein...

  • Protein Structure Prediction Using an Augmented Homology Modeling Method: Key Importance of Iterative-Procedures for Obtaining Consistent Quality Models. McDonald, Shawn; Mylvaganam, Shankari; Shenderovich, Mark; Tseitin, Vladimir; Fisher, Cindy; Raghunathan, Gopalan; Jinhua Zheng; Kodandapani, Ramadurgam; Dudek, Michael; Prabhakaran, Muthuchi-dambaram; Ramnarayan, Kal // Current Proteomics;Oct2005, Vol. 2 Issue 3, p233 

    Deciphering of the human genome and other model genomes presents the challenge of unraveling the gene products that are expressed by these genomes, and identifying the functional role of the expressed proteins. Rapid determination of the three-dimensional (3D) structures of the gene products is...

  • Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells. Muteliefu, Gulinuer; Enomoto, Atsushi; Jiang, Ping; Takahashi, Masahide; Niwa, Toshimitsu // Nephrology Dialysis Transplantation;Jul2009, Vol. 24 Issue 7, p2051 

    Background. Previously, we demonstrated that indoxyl sulphate (IS), a uraemic toxin, induced aortic calcification in hypertensive rats. This study aimed to determine if IS induces the production of reactive oxygen species (ROS) and the expression of osteoblast-specific proteins in human aortic...

  • Predicting protein function. Dove, Alan // Nature Biotechnology;Feb99, Vol. 17 Issue 2, p120 

    Reports on the prediction of biochemical activity of protein based on a data from X-ray crystallography. Determination of the crystal structure of hyperthermophile, Methanoccus jannaschii by expressing a protein; Benefits of studying an organism, extremophiles for protein crystallization.

  • Recent Developments in Structural Proteomics: From Protein Identifications and Structure Determinations to Protein-Protein Interactions. Hsueh-Fen Juan; Hsuan-Liang Liu; Jyh-Ping Hsu // Current Proteomics;Jul2004, Vol. 1 Issue 3, p183 

    The human genome project has opened novel scientific avenues such as structural proteomics. The major challenge in structural proteomics is to predict protein structure-function relationships, including the identification of those proteins whose structures are partially or fully unknown. The use...

  • Cold War Christians and the Spectre of Nuclear Deterrence, 1945-1959. COLEMAN, DAVID // American Historical Review;Apr2015, Vol. 120 Issue 2, p585 

    No abstract available.

  • Conformational thermostabilisation of corticotropin releasing factor receptor 1. Kean, James; Bortolato, Andrea; Hollenstein, Kaspar; Marshall, Fiona H.; Jazayeri, Ali // Scientific Reports;7/10/2015, p11954 

    Recent technical advances have greatly facilitated G-protein coupled receptors crystallography as evidenced by the number of successful x-ray structures that have been reported recently. These technical advances include novel detergents, specialised crystallography techniques as well as protein...

  • Design of novel FN3 domains with high stability by a consensus sequence approach. Jacobs, Steven A.; Diem, Michael D.; Luo, Jinquan; Teplyakov, Alexey; Obmolova, Galina; Malia, Thomas; Gilliland, Gary L.; O'Neil, Karyn T. // PEDS: Protein Engineering, Design & Selection;Mar2012, Vol. 25 Issue 3, p107 

    The use of consensus design to produce stable proteins has been applied to numerous structures and classes of proteins. Here, we describe the engineering of novel FN3 domains from two different proteins, namely human fibronectin and human tenascin-C, as potential alternative scaffold...

  • Decellularized silk fibroin scaffold primed with adipose mesenchymal stromal cells improves wound healing in diabetic mice. Navone, Stefania Elena; Pascucci, Luisa; Dossena, Marta; Ferri, Anna; Invernici, Gloria; Acerbi, Francesco; Cristini, Silvia; Bedini, Gloria; Tosetti, Valentina; Ceserani, Valentina; Bonomi, Arianna; Pessina, Augusto; Freddi, Giuliano; Antonio, Alessandrino; Ceccarelli, Piero; Campanella, Rolando; Marfia, Giovanni; Alessandri, Giulio; Parati, Eugenio Agostino // Stem Cell Research & Therapy;2014, Vol. 5 Issue 1, p1 

    Introduction Silk fibroin (SF) scaffolds have been shown to be a suitable substrate for tissue engineering and to improve tissue regeneration when cellularized with mesenchymal stromal cells (MSCs). We here demonstrate, for the first time, that electrospun nanofibrous SF patches, cellularized...

  • Design of single-layer beta-sheets without a hydrophobic core. Koide, Shohei; Huang, Xiaolin // Nature;1/27/2000, Vol. 403 Issue 6768, p456 

    Reports on the engineering of outer surface protein A (OspA) variants that contain large single-layer beta-sheets by duplicating a beta-hairpin unit within the beta-sheet. Confirmation of the structure of OspA by nuclear magnetic resonance imaging and small-angle x-ray scattering analyses;...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics