TITLE

Color Doppler sonography and angioscintigraphy in hepatic Hodgkin's lymphoma

AUTHOR(S)
Stojković, Mirjana V.; Artiko, Vera M.; Radoman, Irena B.; Knežević, Slavko J.; Lukić, Snezana M.; Kerkez, Mirko D.; Lekić, Nebojsa S.; Antić, Andrija A.; Žuvela, Marinko M.; Ranković, Vitomir I.; Petrović, Milorad N.; Šobić, Dragana P.; Obradović, Vladimir B.; Del Poggio, Paolo; Serafimoski, Vladimir C.
PUB. DATE
July 2009
SOURCE
World Journal of Gastroenterology;7/14/2009, Vol. 15 Issue 26, p3269
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
AIM: To estimate the characteristics of Color Doppler findings and the results of hepatic radionuclide angiography (HRA) in secondary Hodgkin's hepatic lymphoma. METHODS: The research included patients with a diagnosis of Hodgkin's lymphoma with metastatic focal lesions in the liver and controls. Morphologic characteristics of focal liver lesions and hemodynamic parameters were examined by pulsed and Color Doppler in the portal, hepatic and splenic veins were examined. Hepatic perfusion index (HPI) estimated by HRA was calculated. RESULTS: In the majority of patients, hepatomegaly was observed. Lesions were mostly hypoechoic and mixed, solitary or multiple. Some of the patients presented with dilated splenic veins and hepatofugal blood flow. A pulse wave was registered in the centre and at the margins of lymphoma. The average velocity of the pulse wave was higher at the margins (P > 0.05). A continuous venous wave was found only at the margins of lymphoma. There was no linear correlation between lymphoma size and velocity of pulse and continuous wave (r = 390, P < 0.01). HPI was significantly lower in patients with lymphomas than in controls (P < 0.05), pointing out increased arterial perfusion in comparison to portal perfusion. CONCLUSION: Color Doppler ultrasonography is a sensitive method for the detection of neovascularization in Hodgkin's hepatic lymphoma and estimation of its intensity. Hepatic radionuclide angiography can additionally help in the assesment of vascularisation of liver lesions.
ACCESSION #
43702023

 

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