Prion gene haplotypes of U.S. cattle

January 2006
BMC Genetics;2006, Vol. 7, p51
Academic Journal
No abstract available.


Related Articles

  • Prion protein gene (PRNP) polymorphisms in native Chinese cattle. Hui Zhao; Xiao-Yan Wang; Wei Zou; Ya-Ping Zhang // Genome;Feb2010, Vol. 53 Issue 2, p138 

    Polymorphisms in four regions of the bovine prion protein gene (PRNP) confer susceptibility to bovine spongiform encephalopathy (BSE). These polymorphisms include a 23-bp insertion/deletion (indel) in the promoter region, a 12-bp indel in intron 1, an octapeptide repeat or 24-bp indel in the...

  • Association of a Bovine Prion Gene Haplotype with Atypical BSE. Clawson, Michael L.; Richt, Juergen A.; Baron, Thierry; Biacabe, Anne-Gaëlle; Czub, Stefanie; Heaton, Michael P.; Smith, Timothy P. L.; Laegreid, William W. // PLoS ONE;2008, Vol. 3 Issue 3, p1 

    Background: Atypical bovine spongiform encephalopathies (BSEs) are recently recognized prion diseases of cattle. Atypical BSEs are rare; approximately 30 cases have been identified worldwide. We tested prion gene (PRNP) haplotypes for an association with atypical BSE. Methodology/Principle...

  • Identifying Variation in the U.S. Bovine Prion Gene. McGinnis, Laura // Agricultural Research;Jan2007, Vol. 55 Issue 1, p15 

    The article presents information on the identification of the variation in bovine prion gene in the U.S. Bovine spongiform encephalopathy--BSE, or mad cow disease--is a serious threat to the U.S. beef industry. To address these and other questions, ARS scientists at the U.S. Meat Animal Research...

  • PRNP Haplotype Associated with Classical BSE Incidence in European Holstein Cattle. Murdoch, Brenda M.; Clawson, Michael L.; Yue, Samuel; Basu, Urmila; McKay, Stephanie; Settles, Matthew; Capoferri, Rossana; Laegreid, William W.; Williams, John L.; Moore, Stephen S. // PLoS ONE;2010, Vol. 5 Issue 9, p1 

    Background: Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease of cattle. The bovine prion gene (PRNP) contains regions of both high and low linkage disequilibrium (LD) that appear to be conserved across Bos taurus populations. The region of high LD, which spans the...

  • Bovine spongiform encephalopathy associated insertion/deletion polymorphisms of the prion protein gene in the four beef cattle breeds from North China. Zhu, Xiang-Yuan; Feng, Fu-Ying; Xue, Su-Yuan; Hou, Ting; Liu, Hui-Rong; Bell, J. // Genome;Oct2011, Vol. 54 Issue 10, p805 

    Two insertion/deletion (indel) polymorphisms of the prion protein gene ( PRNP), a 23-bp indel in the putative promoter region and a 12-bp indel within intron I, are associated with the susceptibility to bovine spongiform encephalopathy (BSE) in cattle. In the present study, the polymorphism...

  • Polymorphisms of Two Indels at the PRNP Gene in Three Beef Cattle Herds. Alexandre Kerber; Diego Hepp; Daniel Passos; Tania de Azevedo Weimer // Biochemical Genetics;Feb2008, Vol. 46 Issue 1/2, p1 

    Abstract  Bovine spongiform encephalopathy (BSE) is a transmissible fatal neurodegenerative disorder, presenting a characteristic spongiform degeneration of cattle brain due to the accumulation of a pathogenic and protease-resistant infectious protein (prion). Two deletion/insertion...

  • DNA polymorphisms of the prion doppel gene region in four different German cattle breeds and cows tested positive for bovine spongiform encephalopathy. Balbus, N.; Humeny, A.; Kashkevich, K.; Henz, I.; Fischer, C.; Becker, C.-M.; Schiebel, K. // Mammalian Genome;Nov2005, Vol. 16 Issue 11, p884 

    Polymorphisms of the prion protein gene PRNP have been shown to influence the susceptibility/resistance to prion infections in human and sheep. In addition, the T174M polymorphism within the flanking prion doppel gene ( PRND) was thought to be involved in susceptibility to sporadic...

  • Sequence variations of the bovine prion protein gene (PRNP) in native Korean Hanwoo cattle. Sangho Choi; Hee-Jong Woo; Jeongmin Lee // Journal of Veterinary Science;Jun2012, Vol. 13 Issue 2, p127 

    Bovine spongiform encephalopathy (BSE) is one of the fatal neurodegenerative diseases known as transmissible spongiform encephalopathies (TSEs) caused by infectious prion proteins. Genetic variations correlated with susceptibility or resistance to TSE in humans and sheep have not been reported...

  • Deletion/insertion polymorphism of the prion protein gene ( PRNP) in Polish Red cattle, Polish White-backed cattle and European bison ( Bison bonasus L., 1758). Czarnik, U.; Grzybowski, G.; Zabolewicz, T.; Strychalski, J.; Kaminski, S. // Russian Journal of Genetics;Apr2009, Vol. 45 Issue 4, p453 

    The aim of the present study was to identify deletion/insertion polymorphism of the bovine prion protein ( PRNP) gene within the promoter sequence (23 bp indel), intron 1 (12 bp indel) and the 3′ end untranslated region (14 bp indel). The experiment was performed on three groups of animals...

  • Molecular and clinical classification of human prion disease. Jonathan DF Wadsworth; Andrew F Hill; Jonathan A Beck; John Collinge // British Medical Bulletin;Jun2003, Vol. 66 Issue 1, p241 

    While rare in humans, the prion diseases have become an area of intense clinical and scientific interest. The recognition that variant Creutzfeldt-Jakob disease is caused by the same prion strain as bovine spongiform encephalopathy in cattle has dramatically highlighted the need for a precise...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics