Nonsteroidal Anti-Inflammatory Drugs in Orthopaedics

Abdul-Hadi, Omar; Parvizi, Javad; Austin, Matthew S.; Viscusi, Eugene; Einhorn, Thomas
August 2009
Journal of Bone & Joint Surgery, American Volume;Aug2009, Vol. 91-A Issue 8, p2020
Academic Journal
The article focuses on the usage of nonsteroidal anti-inflammatory drugs (NSAIDs) in orthopaedics. It outlines effect of NSAIDs on osseointegration and aseptic loosening, spinal fusion, and fracture-healing. It notes that the prescription of cyclooxygenase-2 (COX-2) inhibitors, plays an important role in bone and soft-tissue healing, and the inhibition of the enzyme can interfere with recovery.


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