A free weekly iron-folic acid supplementation and regular deworming program is associated with improved hemoglobin and iron status indicators in Vietnamese women

Casey, Gerard J.; Phuc, Tran Q.; MacGregor, Lachlan; Montresor, Antonio; Mihrshahi, Seema; Thach, Tran D.; Tien, Nong T.; Biggs, Beverley-Ann
January 2009
BMC Public Health;2009, Vol. 9, p261
Academic Journal
Background: Anemia due to iron deficiency is recognized as one of the major nutritional deficiencies in women and children in developing countries. Daily iron supplementation for pregnant women is recommended in many countries although there are few reports of these programs working efficiently or effectively. Weekly iron-folic acid supplementation (WIFS) and regular deworming treatment is recommended for non-pregnant women living in areas with high rates of anemia. Following a baseline survey to assess the prevalence of anemia, iron deficiency and soil transmitted helminth infections, we implemented a program to make WIFS and regular deworming treatment freely and universally available for all women of reproductive age in two districts of a province in northern Vietnam over a 12 month period. The impact of the program at the population level was assessed in terms of: i) change in mean hemoglobin and iron status indicators, and ii) change in the prevalence of anemia, iron deficiency and hookworm infections. Method: Distribution of WIFS and deworming were integrated with routine health services and made available to 52,000 women. Demographic data and blood and stool samples were collected in baseline, and three and 12-month post-implementation surveys using a population-based, stratified multi-stage cluster sampling design. Results: The mean Hb increased by 9.6 g/L (95% CI, 5.7, 13.5, p < 0.001) during the study period. Anemia (Hb<120 g/ L) was present in 131/349 (37.5%, 95% CI 31.3, 44.8) subjects at baseline, and in 70/363 (19.3%, 95% CI 14.0, 24.6) after twelve months. Iron deficiency reduced from 75/329 (22.8%, 95% CI 16.9, 28.6) to 33/353 (9.3%, 95% CI 5.7, 13.0) by the 12-mnth survey, and hookworm infection from 279/366 (76.2%,, 95% CI 68.6, 83.8) to 66/287 (23.0%, 95% CI 17.5, 28.5) over the same period. Conclusion: A free, universal WIFS program with regular deworming was associated with reduced prevalence and severity of anemia, iron deficiency and hookworm infection when made available to Vietnamese women over a 12-month period.


Related Articles

  • Effect of routine iron supplementation with or without folic acid on anemia during pregnancy. Imdad, Aamer; Bhutta, Zulfiqar A. // BMC Public Health;2011 Supplement 3, Vol. 11 Issue Suppl 3, p1 

    Introduction: Iron deficiency is the most prevalent nutrient deficiency in the world, particularly during pregnancy. According to the literature, anemia, particularly severe anemia, is associated with increased risk of maternal mortality. It also puts mothers at risk of multiple perinatal...

  • Maternal iron supplementation: one size does not fit all. MENON, KAVITHA C. S.; SKEAFF, SHEILA A.; ZODPEY, SANJAY // Current Science (00113891);7/25/15, Vol. 109 Issue 2, p239 

    The article discusses the prevalence of anaemia in women in developing countries due to iron deficiency. Topics include the need to screen pregnant women using hematological indices to diagnose iron deficiency anaemia; use of iron and folic acid supplements by pregnant women to address anaemia...

  • Relative efficacy of micronutrient powders versus iron- folic acid tablets in controlling anemia in women in the second trimester of pregnancy. Choudhury, Nuzhat; Aimone, Ashley; Hyder, S. M. Ziauddin; Zlotkin, Stanley H. // Food & Nutrition Bulletin;Jun2012, Vol. 33 Issue 2, p142 

    Background. Iron deficiency is a major cause of anemia and the most prevalent nutrient deficiency among pregnant women in developing countries. The use of iron and folic acid supplements to treat and prevent irondeficiency anemia has limited effectiveness, mainly due to poor adherence. Home...

  • Dietary recommendations in patients with deficiency anaemia. Santoyo-Sánchez, A.; Aponte-Castillo, J. A.; Parra-Peña, R. I.; Ramos-Peñafiel, C. O. // Revista Medica del Hospital General de Mexico;2015, Vol. 78 Issue 3, p144 

    A diet deficient in iron, vitamin B9 (folic acid) and/or vitamin B12 (cobalamin) can affect erythropoiesis and cause anaemia. Treatment consists in the administration of supplements to compensate for dietary deficiencies and build up body reserves. Pharmacological treatment should be...

  • Mikrositik anemi ile seyreden kombine nutrisyonel anemiler. TÜREDİ YILDIRIM, Ayşen; DEMİRBİLEK, Hüseyin; SAYGI, Semra; ALİOSMANOĞLU, Çiğdem; SÖKER, Murat // Journal of Dr. Behcet Uz Children's Hospital;Apr2013, Vol. 3 Issue 1, p44 

    Objective: Iron deficiency is a leading cause of microcytic anemia for children. On the other hand, B12 deficiency, which is a relatively rare event than iron deficiency, coexists with macrocytic anemia. The purpose of this study was two-fold: first, to measure the frequency of B12 deficiency in...

  • Sources of dietary iron in urban and provincial 4-year-old children in Iran. Zohouri, Fatemeh V; Rugg-Gunn, Andrew J // Asia Pacific Journal of Clinical Nutrition;Jun2002, Vol. 11 Issue 2, p128 

    Iron-deficiency anaemia is prevalent in childhood, especially in developing countries. Nutritional deficiency is one of the main causes of iron-deficiency anaemia, although absorption varies considerably between different dietary items. Information on the sources of iron in young children is...

  • Gastrointestinal parasites in Ugandan cancer patients: a retrospective departmental review. Robinson, A. J.; Katongole-Mbidde, E. // Tropical Doctor;Jul2006, Vol. 36 Issue 3, p188 

    Of all cancer patients, 28% had gastrointestinal parasites of medical importance.

  • Bone Marrow Status of Anaemic Pregnant Women on Supplemental Iron and Folic Acid in a Nigerian Community. Okafor, L. A.; Diejomaoh, F. M. E.; Oronsaye, A.U. // Angiology;Aug1985, Vol. 36 Issue 8, p500 

    The bone marrow status of 31 consecutive pregnant women who had been on supplemental oral iron and folic acid since early pregnancy at the University of Benin Teaching Hospital was assessed later in pregnancy to test the efficacy of oral iron and folic acid in preventing iron deficiency and/or...

  • Nutritional Imbalances: in Anemia. Werbach, Melvyn R. // Townsend Letter;Jan2008, Issue 294, p120 

    The article discusses the contribution of nutrient deficiencies to the development of anemia. Vitamin A deficiency results to the decline of serum which impairs the synthesis of synthesis and sickle cell anemia. Folic acid deficiency develops aplastic and red cell anemia, however, it could be...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics